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Toward a Tobacco-Free Society. Chapter 11. Psychoactive Drugs and Changes in Brain Chemistry. Psychoactive drugs act on one or more neurotransmitters in the brain by increasing/decreasing their concentrations and actions Ex. Dopamine is thought to play a role in reinforcement
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Toward a Tobacco-Free Society Chapter 11
Psychoactive Drugs and Changes in Brain Chemistry • Psychoactive drugs act on one or more neurotransmitters in the brain by increasing/decreasing their concentrations and actions • Ex. Dopamine is thought to play a role in reinforcement • Nicotine raises Dopamine levels much in the same way that Alcohol, Heroin, Amphetamines do
Who Uses Tobacco? • ~15-18% of the U.S. population • ~19% of males and ~15% of females • ~480,000 deaths/year attributable to smoking • On average, smokers die about 10 years earlier than nonsmokers • The more education a person has, the less likely they are to smoke
Why Start in the First Place? • 90% of all new smokers in this country are children and teenagers and 1,300 children and adolescents start smoking every day • Average age to start smoking • 13 for smoking tobacco • 10 for smokeless tobacco • Reasons why young people start smoking • Rationalizing the dangers • Danger is not immediate • Feel invincible • Social representation of smoking as exciting, glamorous or safe
Why People Continue Using Tobacco • Nicotine Addiction • Nicotine = addictive psychoactive drug naturally found in tobacco • Loss of control • On average, smokers can go no longer than 40 min. between doses of nicotine • Tolerance and withdrawal • Symptoms include severe cravings, insomnia, confusion, difficulty concentrating, headache
Why People Use Tobacco • Social and Psychological Factors • Secondary reinforcers are activities the smoker associates with tobacco use
Health Hazards of Smoking Tobacco • Cigarettes contain ~ 600 chemical substances and thousands more are formed as it is burned
Carcinogens and Poisons in Tobacco Smoke • Benzene – found in gasoline/pesticides • Formaldehyde – used in embalming fluid; causes eye irritation and coughing • Arsenic-interferes with our DNA repair mechanisms • Cadmium – found in batteries; damages kidneys and wall of arteries • Ammonia – enhances addictive nature of nicotine • Hydrogen cyanide -damages cilia • Carbon monoxide -Displaces oxygen in red blood cells • Chromium – makes carcinogens stick to DNA • Tar – particulate, sticky matter that forms when a cigarette is burned • Other Additives • Humectants, sugars, bronchodilators, things to make secondhand smoke less obvious
“Light” and Low-Tar Cigarettes • Low-tar, low-nicotine, or filtered cigarettes • There is no such thing as a safe cigarette • Users often smoke more, inhale more deeply, blocking ventilation holes • Less likely to quit than smokers of regular cigarettes • In 2010, federal law prohibited the use of terms such as “light” and “mild”
Menthol Cigarettes • Menthols comprise about 30% of the total cigarette market • Anesthetizing effect of menthol, means smokers inhale more deeply and hold smoke longer in the lungs, causing more damage.
Immediate Effects of Smoking • Nicotine can either Excite or Tranquilize the Nervous System Depending on Dosage and tolerance of the smoker • The beginning smoker often feels dizziness, faintness, rapid pulse, cold, clammy skin, nausea • At low dosages nicotine constricts blood vessels, elevates HR and BP; higher doses can be lethal (mainly for children, overdoses in adults are rare) • Adrenal glands are stimulated to release adrenaline • Can act as a sedative, relieving symptoms of anxiety and irritability • Depresses hunger and dulls taste buds
The Long-Term Effects of Smoking • Cardiovascular Disease • Research indicates that the total amount of tobacco smoke inhaled is a key factor contributing to disease • Coronary heart disease (CHD) causes just as many deaths from smoking as lung cancer • Atherosclerosis leading to angina pectoris and heart attack
The Long-Term Effects of Smoking • Lung Cancer and Other cancers • Research has linked smoking to cancers of the trachea, mouth, esophagus, larynx, pancreas, bladder, kidney, breast, cervix, stomach liver, colon and skin • Chronic obstructive pulmonary disease (COPD) • Emphysema and Chronic bronchitis
Figure 11.1 Annual Mortality Among Smokers Attributable to Smoking
Figure 11.1 Annual Morbidity Among Smokers Attributable to Smoking
Additional Health, Cosmetic, and Economic Concerns • Ulcers • Impotence • Reproductive health problems • Dental diseases • Diminished physical senses • Injuries • Cosmetic concerns (crows feet around eyes and lips) • Economic costs ($5.89/pack or ~ $2,150.00/year)
Other Forms of Tobacco • Spit (smokeless) tobacco • Contains at least 28 chemicals known to cause cancer • Cigars and pipes • Users do not need to inhale in order to ingest nicotine - its absorbed through gums and mouth • Cigars contain more tobacco than cigarettes more nicotine • E-cigarettes • Contain nicotine, other harmful substances
The Effects of Smoking on the Nonsmoker • Environmental Tobacco Smoke (ETS) or Secondhand • Secondhand smoke consists of mainstream smoke (exhaled by smokers) and sidestream smoke (from a burning cigarette, cigar, or pipe) • Sidestream smoke has twice the tar and nicotine,~ 3X the benzo(a)pyrene, CO, and ammonia • EPA designated ETS as a class A carcinogen and Surgeon General has concluded that there is no safe level of exposure to ETS. • ~ 41,000 people die/year from secondhand smoke
Infants, Children, and Secondhand Smoke • Children exposed to ETS are more likely to have • SIDs and low-birth weight • Bronchitis, pneumonia, and asthma • Reduced lung function • Middle-ear infections • Lung cancer, emphysema, and chronic bronchitis later in life
Smoking and Pregnancy • 12-20% of pregnant women smoke • There is increased risk of miscarriage, stillbirth, premature birth, low birth weight, SIDS, and long term impairments in growth and intellectual development
How A Tobacco User Can Quit • The best way to avoid all of the added chemicals in cigarettes is to stop smoking right now!! This very minute!! THE BENEFITS OF QUITTING ARE IMMEDIATE! • Action at many levels • CDC-Tips From Former Smokers • Smokefree.gov • Free telephone quit-lines • 1-800-QUITNOW • Individual action -Talk with your friends and family who have quit smoking and see what helped them, 'quit smoking' products
Benefits of Quitting Smoking • There are benefits of quitting • 20 minutes after quitting, BP and heart rate drop • After 48 hrs. senses (taste, smell) may improve • Within weeks, circulation improves, less wheezing, wounds may heal faster • Within months, lung function improves, less fatigue • Benefits continue for years after quitting!
Toward a Tobacco-Free Society Chapter 11