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Quick quiz on Anti- helminthics

Quick quiz on Anti- helminthics. By Sarah E. Anti- helminthics. Name the ones that treat trematodes . Praziquantel (Major trematode disease= schistosomiasis (snails!) Name the ones that treat cestodes Niclosamide (not in US though) Praziquantel Albendazole for cysticercosis.

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Quick quiz on Anti- helminthics

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  1. Quick quiz on Anti-helminthics By Sarah E.

  2. Anti-helminthics • Name the ones that treat trematodes. • Praziquantel • (Major trematode disease=schistosomiasis (snails!) • Name the ones that treat cestodes • Niclosamide (not in US though) • Praziquantel • Albendazole for cysticercosis

  3. Anti-helminthics • Name the ones that treat nematodes • Mebendazole • Thiabendazole • Albendazole • Pyrantel • Diethylcarbamazine • ivermectin

  4. Anti-helminthics • Which one kills the ova of cestodes? • Praziquantel • Which one is the DOC for filariasis? • Diethylcarbamazine or ivermectin • Which ones can give the mazotti reaction? • Ivermectin, diethylcarbamazine • Which one is the DOC for strongyloides? • ivermectin

  5. Anti-helminthics • Which ones are contraindicated in pregnancy? • Praziquantel, albendazole, pyrantel, ivermectin • Which one is the DOC for cystic hydatid disease? • Albendazole • Which can be used to treat pinworm? • Mebendazole, albendazole

  6. Anti-helminthics • Which is contraindicated in occularcysticercosis? • Praziquantel • Which is contraindicated in occularoncocerciasis? • Diethylcarbamazine • Which can topically treat “creeping eruption” and strongyloidiasis? • thiabendazole

  7. Anti-helminthics • Why is thiabendazole better topically than orally? • Increased absorption orally leads to more toxic effects • Which is contraindicated in meningitis? • Ivermectin • Why? • It affects GABA • Which is thought to block microtubule function? • mebendazole

  8. Anti-helminthics • Which works by increasing Ca2+ permeability? • Praziquantel (also kills ova of cestodes) • Which acts a both a muscle depolarizer and cholinesterase inhibitor? • Pyrantel • Which one stops attachment of the worms to the intestine? • diethylcarbamazine

  9. Anti-helminthics • What is an alternate DOC for nematodes? • Pyrantel • What are the side effects? • Dizziness, drowsiness, GI effects, headache, can’t take it when pregnant • What is the primary DOC for nematodes? • Diethylcarbamazine or ivermectin

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