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Cystic Fibrosis Infertility in Men and Women

Cystic Fibrosis Infertility in Men and Women. Mary Goodman March 15, 2006. Infertility in Males. Although men with Cystic Fibrosis still may have a great sex life, the majority of them are infertile.

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Cystic Fibrosis Infertility in Men and Women

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  1. Cystic FibrosisInfertility in Men and Women Mary Goodman March 15, 2006

  2. Infertility in Males • Although men with Cystic Fibrosis still may have a great sex life, the majority of them are infertile. • 99% of adult males with Cystic Fibrosis are characterized by congenital bilateral absence of vas deferens (CBAVD).

  3. CBVAD • Congenital bilateral absence of the vas deferens • The improper development of the tube through which sperm are released from the testes. • Similar to being born with a vasectomy; you have sperm but pathway to release them is missing. • Causes of CBVAD are genetic mutations and variations in the CF gene.

  4. Female Infertility • Females with CF are less fertile than normal healthy women. • Delayed puberty and amenorrhoea are common due to malnutrition. • Women with CF have a thicker cervical mucus which makes it hard for the sperm to swim through, however not impossible.

  5. Resources • Jarzabek K, Zbucka M, Pepinski W, Szamatowicx J, Domitrz J, Janica J, Wolczynoski S, Szamatoqicz M. 2004. Cystic Fibrosis as a cause of infertility. Reproductive Biology. Vol. 4, No. 2. • www.cysticfibrosismedicine.com • www.healingwell.com/library/cysticfibrosis/info1.asp • www.dnadirect.com/resource/conditions/cystic_fibrosis/faqs_CF_infertility.jsp

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