Understanding Mild Forms of Autism: Link Between Cognition and Mood

1. enhance Milder forms of autism: between cognition and mood Laurens Landeweerd University of Maastricht (Nl), dept of Health Ethics and Philosophy

2. University of Maastricht Department of Health Ethics and Philosophy

3. Thesis:Prenatal genetic diagnosis and the problem of a liberal eugenics • Problematic nature of the absence of ‘identity’ in med. ethics (a general neo-liberalist tendency) • Problematic nature of intergenerational justice on an individual scale

4. Sheffield institute of biotechnology law and ethics (SIBLE) MA in Biotechnology Law and Ethics, course in Moral Theories

5. University of Bristol Centre for ethics in medicine

6. EC-funded project in teaching and research of ethics of biotechnologies Follow-up of BioTethics, only on teaching

7. BioTethics – an introductionLandeweerd, Houdebine, ter Meulen (eds.) 2nd edition. Ponteborboli, Florence, 2006. No image available

8. Enhance ENHANCING HUMAN CAPACITIES: ETHICS, REGULATION AND EUROPEAN POLICY www.enhanceproject.org Coordinator: Ruud ter Meulen

9. Enhancement of: • Cognition • Life span • Mood • Physical performance

10. University of Maastricht: mood enhancement • My first association: • Using drugs that were originally developed for therapy of depression to go beyond normal functioning • Not from (clinically) depressed to happy, but fro existentially troubled to okay

11. Perceived weakness: • Presupposes one line from clinically depressed to normal happy functioning. Mood is wider • What about ‘clinically happy’ (the manic phase in manic depression)? • Should we solve problems of life through medication? • Can one cure ‘life’? • More tantalizing case: tension between happiness, social environment, cognitive advantages.

12. But: contra-intuitive case: Asperger syndrome (and other mild forms of autism) Symptoms • lack of empathy • average to high intelligence • difficulties with social interaction (often leading to social isolation But also • a high ability to concentrate on one thing • Unusual talents or ‘genius’ on specific areas

13. Can one prevent or cure autism? • Medicine: • Early experiments with marihuana and LSD • Change of perception and social behavior • Genetic selection • 9 out of 10 times, twins both exhibit the condition: • Likely hereditary nature of autistic disorders/conditions • Pre-selection and in utero germ line intervention might theoretically be feasible

14. Mild autism spectrum disorders social disability or cognitive super-ability • Hyperlexia: speech disability, reading super ability • Pervasive developmental disorder: social and communicative disorder • High functioning autism: talentedness on specific area but social dysfunction • Asperger syndrome: talentedness on specific area but awkwardness

15. Classical pre-definition picture Geeks / nerds

16. Some talents associated with mild autism spectrum disorders: • Musical talents • Mathematics/physics (exact sciences) • Logics/philosophy • IT / computers

18. People that allegedly suffer(ed) a form of autism: • Isaac Newton • Bela Bartok • Ludwig Wittgenstein • Salvador Dali • Bill Gates • Bill Evans • Andy Warhol • Albert Einstein

19. 5.64Hier sieht man, daß der Solipsismus, streng durchgeführt, mit dem reinen Realismus zusammenfällt. Das Ich des Solipsismus schrumpft zum ausdehnungslosen Punkt zusammen, und es bleibt die ihm koordinierte Realität 5.633 Wo in der Welt ist ein metaphysisches Subjekt zu merken? Du sagst, es verhält sich hier ganz, wie mit Auge und Gesichtsfeld. Aber das Auge siehst du wirklich 'nicht'. Und nichts 'am Gesichtsfeld' läßt darauf schließen, daß es von einem Auge gesehen wird. 5.6331Das Gesichtsfeld hat nämlich nicht etwa eine solche Form:

20. Being / having traits • Helmut Plessner: nature of human existence as eccentric positionality • Martin Heidegger: ontological differentiation between oneself as a being, and oneself as having a relation to that being from within that being • Husserl: anti-psychologism /anti- reductionism • Kierkegaard: the self as a relationship of oneself to one-self that although taking place within oneself, is based in one’s relationship to the other person(s)

21. “Autism isn't something a person has, or a "shell" that a person is trapped inside. There's no normal child hidden behind the autism. […] It is not possible to separate the autism from the person - and if it were possible, the person you'd have left would not be the same person you started with”

22. “I do not wish to be 'cured' from my autism, and many autistic persons who are able to communicate their feelings, say the same thing […] If it were possible to remove autism from a person, you would get a different person. A person who, perhaps, fits in better with his surroundings. Maybe a person who abides by the rules of society more. A person who does not stick out. That person will look identical to the previous one, but will be a different person nonetheless.”

23. So, is one allowed to create a super genius on purpose? • Cognitive enhancement • Possible alleviation of the social handicap

24. Aiming at autistic disorders: • A possible enhancement of certain cognitive skills • Avoiding or curing autistic disorders: • when it is a normal variant, this would constitute a form of eugenics/enhancement

25. mood and enhancement Depression » normal functioning Normal functioning » enhanced functioning

26. Mood • General problems with the term ‘enhancement’: • Presupposition of an objective scale from bad to normal to enhanced • Problematic distinction between therapy and enhancement, and between enhancement and dyshancement.

27. Scientism: • Objectivity of science • presupposition of objective traceability of normative terms • Good genes or features vs. bad genes or features as objectively given

28. Following from scientism • Objective distinction between therapy and enhancement • Isn’t prenatal diagnosis in general already enhancement? • What about plastic surgery? • Objective definition of what is enhanced, what is better. But what’s the distinction between enhancement and dyshancement?

29. Conceptual problems • Old-fashioned nature of the Boorse-Engelhardt-controversy: normative vs. descriptive nature of a dysfunction has been debated quite extensively. And whether the one or the other is right, does this have any bearing on our ethical conclusions? • Highly speculative nature of the case: prevention or specification of the birth of these people isn’t possible, nor are there any cures or enhancements for the features in question • Cognition rather than mood as the main feature of mild autism spectrum disorders • Do ‘mood’ and ‘enhancement’ fit togetherat all?

30. www.enhanceproject.org