A Brief Alleviation For Tinnitus Sufferers
For at least 50 million Americans, there's nothing as quiet and peace, because each second of silence is accompanied with a persistent ringing in the ears. Tinnitus, which has no cure, is a problem that affects individuals of all ages. But now there's a treatment. From the sensory system, sound waves enter hairs stimulate that get carried along nerve pathways into the brain. People always used to believe that the hair follicles were the parts in the ear and also that nerve fibers never died until after the hair follicles had been gone. Interview Highlights On what's really happening when your ears are still ringing. Susan Shore: What occurs initially for people that have tinnitus is that the hair follicles or the nerve fibers become ruined. And that means that they can't connect with all the cells from the mind . This is known as deafferentation. The cells begin to fire quickly, and they start to synchronize with each other, as if there were sound there. However there isn't a noise there. And so that's what we figured out over the last ten years or so, the cells which are accountable for the tinnitus and sending this phantom signal to the rest of the mind reside in the very first region of the brain that gets input in the ear. It's called the cochlear nucleus. On a treatment for tinnitus. Susan ShoreWe figured out by studying spike time independent in these fusiform cells that when we provoked those cells with a certain order we can depress the firing rate of the neurons. We can desynchronize the circuit, and we can get pigs that we had been recording from. On why you might have difficulty hearing people talk when it is noisy. Charles Liberman: Basically, what we've discovered recently is that using a standard audiogram, there may be levels of damage to the nerve fibers that take the info in the sensory cells into the brain. So that's why it's called hearing loss. On temporary hearing loss from a event like a concert can result in permanent damage. Charles Liberman: later you hear a tiny ringing in your ears, or you feel like you have cotton in your ears, and Should you expose yourself to sound, you have a hearing loss which could be quantified by an audiologist. It might recover, but what we've shown in animal models is the fact that noise exposures that trigger this type of hearing loss that is reversible as measured by the audiogram can cause irreversible loss of nerve pathways. And that is the hearing loss idea that is hidden . You believe you dodged the bullet. Your thresholds went back to usual. But perhaps every time that happens, you've lost a nerve fibers. And as time goes on, that might slowly cause the sorts of deafferentation issues that Susan referred to this can ultimately trigger issues. On fixing hearing loss that is hidden. Charles Liberman: Some of the interesting things about hearing loss that is hidden is initially that the damage is the so-called synapses between the hair cells, the loss of the relations and the neural pathways. And at that time, should you type of grab it early, we and others have already shown in animal models we understand what molecules to send to the internal ear to induce the nerve pathways to ship out new connections and to create new functional connections.
32 views • 2 slides