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NON-SPECIFIC URETHRITIS

NON-SPECIFIC URETHRITIS. Danny A. Hermawan, Dip Derm Medical Faculty of Ukrida JAKARTA. Sinonim NSGI = Non Specific Genital Infection NSU = Non Spesific Urethritis NGGI = Non Gonococcal Genital Infection NGU = Non Gonococcal Urethritis Definisi

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NON-SPECIFIC URETHRITIS

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  1. NON-SPECIFIC URETHRITIS Danny A. Hermawan, Dip Derm Medical Faculty of Ukrida JAKARTA

  2. Sinonim NSGI = Non Specific Genital Infection NSU = Non Spesific Urethritis NGGI = Non Gonococcal Genital Infection NGU= Non Gonococcal Urethritis Definisi NSGI= infeksi pada genital tanpa ditemukan kuman spesifik NSU= adalah radang uretra tanpa ditemukan kuman spesifik NGGI= infeksi genital bukan karena kuman gonokok NGU= radang uretra bukan karena kuman gonokok

  3. “Kuman Spesifik” • Kuman yang dapat dideteksi dengan pemeriksaan laboratorium sederhana/ biasa Yaitu : • Gonokok • Candida albicans • Trichomonas vaginalisSpesific Urethritis • Escherichia coli

  4. Epidemiologi • NSU : UGO = 2 : 1 • Beberapa negara tertentu seperti: AS, Eropa,Indonesia = 1 : 1 • Sosial ekonomi  • Usia > tinggi • ♂ > ♀ • Heterosex > homosex

  5. Etiologi Utama : • Chlamydia trachomatis (serotype D-K) • Ureaplasma urealiticum • Mycoplasma hominis • Gardnerella vaginalis • Bakteri: Staphylococcus, Diphtheroid • Alergi: kimia, sekret partner • Virus: HSV

  6. Simtomatologi ♂(Pria) : • Masa tunas 2 – 3 minggu  coitus suspectus , gejala ringan ( < GO) • Disuria ringan (anyang-anyangan) + gatal M.U.E • Polakisuria • Duh tubuh seropurulen (encer) • Komplikasi: prostatitis, vesikulitis, epididimitis, striktura uretra

  7. Simtomatologi ♀ (Wanita) : • Masa tunas ??, gejala sangat ringan atau tanpa gejala (~ GO) • Disuria ringan • Fluor albus ringan • Nyeri pelvis • Dyspareunia • Kolposkopi: tanda-tanda servisitis + folikel-folikel mudah berdarah • Komplikasi: bartholinitis, sistitis, salpingitis (PID), proktitis, peritonitis & • perihepatitis (=penyakit Fitz Hugh Curtis)

  8. Excrete Kuman GO (-) Leucocytes (+) > 4/ lpb k. GO (+) Gonorrhoea NGU Specific Bactery (-) Specific Bactery (+) e.g. Tr. vaginalis, E. coli, C. albicans NSU SU Diagnosis • Laboratorium Sederhana

  9. Diagnosis • Laboratorium Lengkap (Complete Laboratory Test) • Embrio Ayam • McCoy Cell (Biakan Sel Hela 229) • Immunofluoresens  serotipe Diagnosis Banding • UGO Kultur Chlamydia trachomatis

  10. Terapi • Golongan Tetracycline • Tetracycline HCl 4 x 500 mg selama 1 mgg 4 x 250 mg selama 2 mgg • Oxytetracycline 4 x 250 mg selama 2 mgg • Doxycycline (Vibramycine) 1 x 200 mg selama 1 mgg dst. 2 x 100 mg selama 1 – 2 mgg • Minocycline (Minocin) 1 x 200 mg dst. 2 x 100 mg selama 1 – 2 mgg • Golongan Erythromycin • Erythromycin (Erythrocin) 4 x 500 mg selama 1 minggu 4 x 250 mg selama 2 minggu • Golongan Sulfa-Trimetoprim 2 x 2 tab selama 1 – 2 minggu (Bactrim, Septrin) • Golongan Spiramisin 4 x 500 mg selama 1 minggu (Rovamycine)

  11. Prognosis • Umumnya baik, tetapi pada terapi yang inadekuat akan residif

  12. ~ Thank You ~

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