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Understanding Human Body Geography: Spatial Organization and Disease Spread

Explore the importance of spatial contiguity in the human body, how diseases spread through neighboring regions, and the impact of location on detection and treatment. Discover how different systems are spatially organized and if common reference points exist. Learn about anatomic regions, lesion locations in the colon, and mapping human genes.

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Understanding Human Body Geography: Spatial Organization and Disease Spread

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  2. Why a geographic perspective of the human body? • Spatial Contiguity is important • Different body “systems” have a spatial organization • Disease spreads to neighboring regions or along networks • Location affects ability to detect and treat

  3. …but everyone’s “base map” is different …can we find common reference points?

  4. Anatomic Regions & Lesion of the Colon 26 cm Anterior Distal Sigmoid Rectosigmoid junction Rectosigmoid Junction 18 cm Anterior Periteoneal Rectum Distance 13 cm Denonvillier’s Fascia Peritoneal Reflection Dentate Line Peritoneal Reflection Anterior AnoRectum Dentate Line 2 cm Anterior Posterior Right Left Left Anterior Right Left Posterior

  5. Mapping the Gene The starting and ending locations of human genes are known

  6. Mapping the Gene chromosome Genes act in a coordinated fashion based on their spatial organization

  7. No scale is too small No scale is too small No scale is too small No scale is too small No scale is too small No scale is too small

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