1 / 14

CELL an interdisciplinary investigation into adult stem cell behaviour

CELL an interdisciplinary investigation into adult stem cell behaviour. Mark d’Inverno dinverno@gold.ac.uk Goldsmiths College University of London. The CELL Project Wellcome Trust. Jane Prophet Neil Theise Mark d’Inverno Rob Saunders Peter Ride. Traditional View of Cell Lineages.

wilton
Download Presentation

CELL an interdisciplinary investigation into adult stem cell behaviour

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. CELL an interdisciplinary investigation into adult stem cell behaviour Mark d’Inverno dinverno@gold.ac.uk Goldsmiths College University of London

  2. The CELL ProjectWellcome Trust Jane Prophet Neil Theise Mark d’Inverno Rob Saunders Peter Ride

  3. Traditional View of Cell Lineages Differentiated Cell Stem Cell

  4. A New View of Cell Lineages Differentiated Cell Stem Cell

  5. Computational Agents • Autonomous • Agents require no intervention • Agents create their own goals • Situated, embodied, sensitive and active • Agents sense their environment • Agents act upon their environment • Interactive • Agents interact with other agents

  6. Problems for Stem Cell Researchers • Problems performing experiments • Impossible to track stem cells in the body • Slides are manipulated images of dead tissue • Experiments can only reveal one fate • Problems working in the field of research • Little consensus on basic terms • Poor conceptual modelling

  7. Agent-based Simulations • consistent with lab - predictions • biological intuitive • visualisation is trojan horse • conceptual framework • aunt sally Towards tool for biologists DEMO DEMO Circular Niche Linear Niche

  8. CELL - role of artists Staining Space by Jane Prophet

  9. Biologists reaction to Model Nature “Cells fulfil all the criteria necessary to be considered agents within a complex system ... they self-organize with external planning. What emerges ...” Now you see it, now you don’t. Neil D. Theise Nature 435, 1165, 2005 interdisciplinary research?

  10. Research Clusterinterdisciplinary.co.uk • UK-based IR community • centred on design • why, when, how and who? • funded jointly by arts and science research councils • theory/practice • academic/commercial • agents as metaphor and language for interdisciplinary design • process based

  11. Reflections language personal qualities social engineering teams responsibility map IR process re-negotiate goals evaluating creativity and innovation discipline change Goldsmiths Digital Studios

  12. Thanks Neil Theise Jane Prophet Peter Ride Mark Kirkland Jon McCormack Alan Dorin Ingo Roeder’s Group Dave Winkler’s Group University of Westminster Wellcome Trust AHRB EPSRC British Academy HEFC

More Related