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Development of GI system. 陳建榮. http://web.nchu.edu.tw/pweb/index2.php?pid=75. GI system: Primitive Gut Morphogenesis Foregut Midgut Hindgut Foregut embryology Midgut embryology Hindgut embryology . Formation of primitive gut. Head fold, tail fold and lateral fold Foregut Midgut
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Development of GI system 陳建榮 http://web.nchu.edu.tw/pweb/index2.php?pid=75
GI system: • Primitive Gut Morphogenesis • Foregut • Midgut • Hindgut • Foregut embryology • Midgut embryology • Hindgut embryology
Formation of primitive gut • Head fold, tail fold and lateral fold • Foregut • Midgut • Hindgut
The primitive gut: • Foregut 前腸 • oesophagus • stomach(S) • proximal half of the duodenum (PD), • liver and pancreas. • Midgut 中腸 • distal half of the duodenum(DD) • jejunum(J), • ileum(I), • cecum(C), • appendix, • ascending colon and the right 3/4 of the transverse colon. • Hindgut 後腸 • left 1/4 of the transverse colon • the descending colon • sigmoid colon • the rectum(R) down to the ano-rectal line (the endoderm-ectoderm junction).
The blood supply: • Foregut : celiac artery • Midgut :superior mesenteric artery • Hindgut :inferior mesenteric artery • The venous drainage of the gut : • Foregut : portal vein • Midgut : superior mesenteric vein • Hindgut :inferior mesenteric vein.
GI system: • Primitive Gut Morphogenesis • Foregut Embryology • Development of stomach • Development of mesentery • Liver morphogenesis • Pancrease morphogenesis • Midgut embryology • Hindgut embryology
Development of stomach • Stomach: • Clock wise 90 • Greater curvature of stomach胃大彎 • Lesser curvature of stomach胃小彎 • Vagus n.
GI system: • Primitive Gut Morphogenesis • Mesentery morphogenesis • Dorsal mesentery背總腸繫膜 • Ventral mesentery腹總腸繫膜 • Foregut Embryology • Midgut embryology • Hindgut embryology
網膜孔 網膜囊
THE MESENTERY:-ventral mesentery: • -falciform lig.鐮狀韌帶 • -lesser omentum小網膜 • -coronary lig.冠狀韌帶 • -triangular lig.三角韌帶 • -dorsal mesentery: • Mesogastrium : greater omentum大網膜, omentum bursa網膜囊 • Mesoduodenum十二指膜系膜 • mesentery proper (distal duodenum, jejunum and ileum), • mesocolon 結腸系膜 • Mesorectum直腸系膜
5 weeks 4 weeks • Development of liver: • Hepatic diverticulum肝憩室 • Hepatic cords 肝索 • Gallbladder膽囊 • Ventral pancreatic bud腹側胰芽 5 weeks 6 weeks
Development of pancrease • Dorsal pancreatic bud背側胰芽 • Body and tail of pancrease, accessory pancreatic duct • Ventral pancreatic bud腹側胰芽 • Uncinate process of pancrase, main pancreatic duct
Development of spleen Accessory spleen副脾
GI system: • Primitive Gut Morphogenesis • Foregut Embryology • Midgut embryology • Rotation of midgut loop • Retum of midgut to abdomen • Fixation of intestine • Cecum and appendix • Hindgut embryology
6 weeks Rotation of midgut loop - Counterclock wise 90 10 weeks Retum of midgut to abdomen 11 weeks
Nonrotation of midgut Mixed rotation and volvulus Reversed rotation Internal hernia Midgut volvulsu
GI system: • Primitive Gut Morphogenesis • Foregut Embryology • Midgut embryology • Hindgut embryology • Partitioning of cloaca泄殖腔 • Urorectal septum泌尿直腸隔 • Cloaca泄殖腔 • Urogenital sinus泌尿生殖竇 • Anal canal肛管
Anal canal 恥狀線 原肛
肛門會陰瘻管 直腸陰道瘻管 直腸尿道瘻管