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Krebs Cycle

Krebs Cycle. Monika Siekelova. Anaerobic and Aerobic Respiration. Glycolosis can occur without oxygen The basis of anaerobic cell respiration Pyruvate produced in glycolysis can only be oxidized further using energy if oxygen is present. This occurs in the mitochondrion

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Krebs Cycle

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  1. Krebs Cycle Monika Siekelova

  2. Anaerobic and Aerobic Respiration • Glycolosis can occur without oxygen • The basis of anaerobic cell respiration • Pyruvate produced in glycolysis can only be oxidized further using energy if oxygen is present. • This occurs in the mitochondrion • First stage is called link reaction • The enzymes in the mitochondrion then catalyze the Krebs Cycle

  3. The Link Reaction • Pyruvate from glycolysis is absorbed by the mitochondrion. • Enzymes in the matrix of the mitochondrion remove hydrogen and carbon dioxide from the pyruvate • The hydrogen is accepted by NAD+. • This is oxidation • Removal of carbon dioxide is decarboxylation.

  4. The Krebs Cycle • First reaction • Acetyl group is transferred from acetyl CoA to a four-carbon compound to form a six-carbon compound • There are three types of reactions involved • Carbon dioxide is removed in two reactions. These are decarboxylations. The carbon is a waste product

  5. continued • Hydrogen is removed in four of the reactions. These are oxidations. In three, the hydrogen is accepted by NAD+ in the other the FAD accepts it. These reactions release energy which is later released by the electron transport chain and used to make ATP • ATP is produced directly in one of the reactions. This is called substrate-level phosphorylation.

  6. animation • Krebs Cycle

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