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Heterozygous for all alleles in MHC II

Heterozygous for all alleles in MHC II. DRA-m or p DRB1-m DRA-m or p DRB1-p DRA-m or p DRB3,4, or 5 m DRA-m or p DRB3,4, or 5 p DQA-m DQB-m DQA-p DQB-p DQA-m DQB-p DQA-p DQB-m DPA-m DPB-m DPA-p DPB-p DPA-m DPB-p DPA-p DPB-m.

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Heterozygous for all alleles in MHC II

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  1. Heterozygous for all alleles in MHC II DRA-m or p DRB1-m DRA-m or p DRB1-p DRA-m or p DRB3,4, or 5 m DRA-m or p DRB3,4, or 5 p DQA-m DQB-m DQA-p DQB-p DQA-m DQB-p DQA-p DQB-m DPA-m DPB-m DPA-p DPB-p DPA-m DPB-p DPA-p DPB-m Makes 12 (and some 16) “HLA heterozygous individuals can express up to six class I and eight class II” - quote in Ch 3 conflicts with Figure A3.9 and my calculations

  2. T cell lineage (Chapter 5) Rearrangement order Outcome   and  are rearranged ---> cell   and  are rearranged ---> cell   and  are rearranged ---> cell   and  are rearranged ---> cell   and  are rearranged ---> cell   rearranged ( rearranged&excised) ---> cell   and  are rearranged ---> cell   and  are rearranged ---> cell   and  are rearranged ---> cell   and  are rearranged ---> cell   rearranged ( rearranged&excised) ---> cell

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