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V L. V H. Influenza antigen. Immunogenicity vs. Antigenicity. Induce . Combine. Small molecules called haptens are Immunogenic but not Antigenic. Epitopes. What do you predict about the ability of these loops to interfere with binding?. complementarity determining region. CDR:. V L.
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VL VH Influenza antigen
Immunogenicity vs. Antigenicity Induce Combine
Small molecules called haptens are Immunogenic but not Antigenic
What do you predict about the ability of these loops to interfere with binding?
VL VH Complex pulled apart to see complementary surfaces Flu antigen
Lysozyme abs: flat, undulating Small molecules: deeper pockets HA peptide Phos choline ssDNA
HIV Protease in its Ab binding pocket
Unbound Antibody Antibody bound to antigen Conformational Change upon binding Ag
SC: 5 Ig Like domains S-S_ to Fc receptor Proteolytically cleaved