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C-C Bond Activation Through b -Carbon Elimination

C-C Bond Activation Through b -Carbon Elimination. Introduction C-C activation of alcohol Decarboxylation Decarbonylation Retro reactions. Wang Chao 2012.3.17. Introduction. Maruoka: J. Am. Chem. Soc. 1998, 120, 10790-10791. J. Am. Chem. Soc. 2001, 123, 10407-10408.

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C-C Bond Activation Through b -Carbon Elimination

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  1. C-C Bond Activation Through b-Carbon Elimination Introduction C-C activation of alcohol Decarboxylation Decarbonylation Retro reactions Wang Chao 2012.3.17

  2. Introduction

  3. Maruoka: J. Am. Chem. Soc. 1998, 120, 10790-10791

  4. J. Am. Chem. Soc. 2001,123, 10407-10408

  5. Shi: J. Am. Chem. Soc. 2011, 133, 15244–15247

  6. alkenylation from C-C cleavage was much faster than from direct CH activation sequential C-C bond cleavage/C-H activation in one pot

  7. Angew. Chem. Int. Ed. 2007, 46, 2643 –2645 Chem. Asian J. 2009, 4, 1217 – 1220

  8. J. AM. CHEM. SOC. 2006, 128, 2210-2211

  9. Angew. Chem. Int. Ed. 2011, 50, 3294 –3298 Org. Lett., Vol. 10, No. 6, 1191-1193

  10. Org. Lett., Vol. 5, No. 17, 2997-2999

  11. Hayashi: J. AM. CHEM. SOC. 2007, 129, 14158-14159

  12. Hayashi: Angew. Chem. Int. Ed. 2008, 47, 1447 –1449

  13. J. AM. CHEM. SOC. 2003, 125, 8862-8869

  14. Cramer: Angew. Chem. Int. Ed. 2009, 48, 6320 –6323 Murakami: Chem. Eur. J. 2009, 15, 12929 – 12931

  15. Cramer: J. AM. CHEM. SOC. 2010, 132, 5340–5341

  16. Murakami: J. AM. CHEM. SOC. 2005, 127, 6932-6933

  17. Murakami: J. AM. CHEM. SOC. 2007, 129, 12086-12087

  18. Murakami: J. AM. CHEM. SOC. 2007, 129, 12086-12087

  19. Decarboxylation Gooßen: Science 313, 662 (2006) Chem. Soc. Rev., 2011, 40, 5030–5048

  20. Summary and Perpective: b-carbon elimination: Aryl, benzyl, Allyl, alkynyl, cyclobutanol Substrate-controlled Other C-C activation systems: Decarbonylation, Cyclopropane, ArCN…

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