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Biology

DNA Replication. Biology. Itinerary. Topics for today Review DNA Replication Overview In Detail. Review. Name the four classes of biomolecules. Review. Name the four classes of biomolecules Define ‘monomer’ and ‘polymer.’. Review. Name the four classes of biomolecules

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Biology

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  1. DNA Replication Biology

  2. Itinerary Topics for today Review DNA Replication Overview In Detail

  3. Review Name the four classes of biomolecules

  4. Review Name the four classes of biomolecules Define ‘monomer’ and ‘polymer.’

  5. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide?

  6. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide? • What are the three components of a nucleotide?

  7. Structure of DNA/RNA (1) Three Components Phosphate Group ‘Pentose Sugar’ Nitrogenous base

  8. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide? • What are the three components of a nucleotide? • What is the difference between the purines and the pyrimidines?

  9. Structure of DNA/RNA (8) You need to remember these!

  10. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide? • What are the three components of a nucleotide? • What is the difference between the purines and the pyrimidines?

  11. Structure of DNA/RNA (3) Deoxyribose and Ribose are both 5 carbon sugars

  12. Review • Name the four classes of biomolecules • Define ‘monomer’ and ‘polymer.’ • What is a nucleotide? • What are the three components of a nucleotide? • What is the difference between the purines and the pyrimidines? 6. Base Pairing

  13. Gary Coleman

  14. Gary Coleman Guanine-Cytosine

  15. Gary Coleman Guanine-Cytosine

  16. Gary Coleman Alex Trebek Guanine-Cytosine Adenine-Thymine

  17. DNA Replication- Overview (1) In Text- p 298

  18. DNA Replication- Overview (1) In Text- p 298 Step 1: The Double Helix is unzipped

  19. DNA Replication- Overview (1) In Text- p 298 Step 1: The Double Helix is unzipped Step 2: Each strand directs the synthesis of two new strands

  20. DNA Replication- Overview (1) In Text- p 298 Step 1: The Double Helix is unzipped Step 2: Each strand directs the synthesis of two new strands Step 3: The individual nucleotides are connected to form two new strands

  21. DNA Replication- Overview (2)

  22. DNA Replication- Overview (3)

  23. DNA Replication- Overview (4)

  24. DNA Replication- Overview (5)

  25. Semiconservative Replication (1) Process of DNA replicationis called ‘semiconservative replication

  26. Semiconservative Replication (2) Process of DNA replicationis called ‘semiconservative replication Make sure you know this term. You’ll see it again!

  27. Semiconservative Replication (3) Process of DNA replicationis called ‘semiconservative replication This means that in each new double helix of DNA, one strand was from the parent.

  28. Semiconservative Replication (4)

  29. Semiconservative Replication (5)

  30. Semiconservative Replication (6)

  31. Semiconservative Replication (7) How do we know that DNA replicates with a ‘Semiconservative’ nature?

  32. Semiconservative Replication (7) How do we know that DNA replicates with a ‘Semiconservative’ nature? Any ideas?

  33. Semiconservative Replication (7) How do we know that DNA replicates with a ‘Semiconservative’ nature? Any ideas? Meselson-Stahl experiment tested the three hypotheses for DNA replication

  34. Semiconservative Replication (8)Meselson-Stahl Experiment

  35. Semiconservative Replication (8)Meselson-Stahl Experiment Where is the 15N found?

  36. Semiconservative Replication (9)Meselson-Stahl Experiment

  37. Semiconservative Replication (10)Meselson-Stahl Experiment

  38. Semiconservative Replication (11)Meselson-Stahl Experiment

  39. DNA Replication Remember, DNA replication is the process of making copies of DNA.

  40. DNA Replication Remember, DNA replication is the process of making copies of DNA. When would the cell do this?

  41. DNA Replication Remember, DNA replication is the process of making copies of DNA. When would the cell do this? Now we need to look at the specifics of DNA replication, and the enzymes involved in each step

  42. But First, What’s an Enzyme?

  43. But First, What’s an Enzyme? A type of Protein

  44. But First, What’s an Enzyme? A type of Protein Text Definition: A class of proteins serving as catalysts, chemical agents that change the rate of a reaction without being consumed within the reaction

  45. Step 1: Separation of the Double Helix

  46. Step 1: Separation of the Double Helix • DNA Helicase unwinds the double helix • The site where the enzyme begins replication is called the origin of replication.

  47. Step 1: Separation of the Double Helix • DNA Helicase unwinds the double helix • The site where the enzyme begins replication is called the origin of replication. • In Prokaryotes (Bacteria), there is a single origin; in eukaryotes, there are thousands

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