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MALARIA!!!

MALARIA!!!. Like the most awesome vector-borne infectious disease caused by protozoan parasites EVER!!!. What is it and Where can I get it?. Is a vector-borne infectious disease caused by protozoan parasites

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MALARIA!!!

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  1. MALARIA!!! Like the most awesome vector-borne infectious disease caused by protozoan parasites EVER!!!

  2. What is it and Where can I get it? • Is a vector-borne infectious disease caused by protozoan parasites • Malaria is one of the most common infectious diseases and an enormous public-health problem. • The parasites multiply within red blood cells, causing symptoms which I will explain shortly • It is widespread in tropical and subtropical regions, including parts of the Americas, Asia, and the eBay for illness AFRICA!!!

  3. How it Spreads • Malaria parasites are transmitted by female Anopheles mosquitoes.

  4. Main Types of MALARIA!!! • Plasmodium Falciparum – 80% of infections and 90% cause of death, found mostly in SSA • Plasmodium Malariae – causes fevers that reoccur at 3 day intervals • Plasmodium Ovale – least sever and dangerous • Plasmodium Vivax – deadliest of the four, you get it you have a 75% chance of dieing with treatment.

  5. Symptoms • fever, shivering, arthralgia (joint pain), vomiting, anemia caused by hemolysis (explosion of red blood cells, hemoglobinuria (increased levels of plasma in urine), and convulsions. • In Children: cognitive impairments, coma and sudden violent death…yes, as a symptom…well it lets the medical examiner know what killed you, symptom of C.O.D.

  6. Symptoms Continued • classical symptom of malaria is cyclical occurrence of sudden coldness followed by rigor and then fever and sweating lasting four to six hours, occurring every two days in P. vivax and P. ovale infections, while every three for P. malariae. P. falciparum can have recurrent fever every 36-48 hours or a less pronounced and almost continuous fever.

  7. Pathogenesis • Within 30 minutes of being introduced into the human host, they infect hepatocytes (cytoplasmic mass of the liver), multiplying asexually and asymptomatically for a period of 6–15 days. • Despers from the liver in the form of thousand of merozoites which infect red blood cells

  8. Pathogenesis Continued • Multiply within the red blood cells then cause them to VIOLENTLY EXPLODE!!!

  9. Treatment • Chloroquine is very cheap and, until recently, was very effective, which made it the anti-malarial drug of choice for many years in most parts of the world. However, resistance of Plasmodium falciparum to chloroquine has spread recently from Asia to Africa, making the drug ineffective against the most dangerous Plasmodium strain.

  10. More Treatment for this Wonderful Disease • drugs such as quinine and amodiaquine are time tested and effective, not for DRM. • All available drugs include Artemether-lumefantrine, Artesunate-amodiaquine, Artesunate-mefloquine, Artesunate-Sulfadoxine, pyrimethamine, Atovaquone-proguanil, Malarone, Quinine, Chloroquine, Cotrifazid, Doxycycline, Mefloquine, Primaquine, Proguanil, Sulfadoxine-pyrimethamine, Hydroxychloroquine.

  11. Even More Treatment • Extracts of the plant Artemisia annua, containing the compound artemisinin or semi-synthetic derivatives offer over 90% efficacy rates, RECEIVED OFFICIAL WHO (do you know what the WHO is? Who’s the WHO)

  12. Prevention • INSECT REPLEANT • MOSQUITO NETTING FOR SPEELPING QUARTERS • NOT GOING TO SUB SAHARAN AFRICA, especially the DRC, OR WHAT WAS FORMERLY FRENCH INDO-CHINA

  13. I Wish I was in DIXIE… • The Epidemic this is and was malaria spread through camps located next to stagnant swamps teeming with anopheles mosquito. Although treatment with quinine reduced fatalities, malaria nevertheless struck approximately one quarter of all servicemen • So still wish you were in DIXIE?

  14. Civil War Malaria • Surgeons from both sides of the Civil War called malaria "ague", "shakes", or "intermittent fever", the illness accounted for 20 percent of all sickness during the war. • people believed malaria was caused by poisonous vapors emanating from ponds and swamps…seems to be a common theme in history, if it kills you then it has to be caused by vapors!!!

  15. Obviously you have never been to China… • First documented cases of Malaria are from China in 2700. • Nothing to do with China but still random – Malaria comes from mal'aria which means bad or evil air. • Kills over 5000 Africans every day…SSAs.

  16. PICTURE TIME So you might want to advert your eyes or not, they’re your eyes.

  17. So Malaria doesn’t have cool pictures like Small Pox so you can look again… Malaria is still awesome

  18. Because of areas like this ↓

  19. And this ↓

  20. This too ↓ They look happy wait till they die of Malaria

  21. Children begin to look like this ↓

  22. Then they begin to look dead ↓

  23. And fields as below Notice the absence of workers.

  24. Resistance of Malaria

  25. What we have learned • Stay away from tropical and sub-tropical areas • Stay away from stagnant water sources • When traveling to tropical/sub-tropical areas bring the following: • Insect repellant • Mosquito netting • Lots of Drugs • A bible, makes for an effective fly swatter.

  26. And that’s why Malaria is the… …most awesome vector-borne infectious disease caused by protozoan parasites EVER!

  27. Can I hear a “HUZZA” for Malaria? Well can’t blame me for being hopeful…

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