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Tracking the Spread of Antibiotic Resistance . SBI3C: Microbiology Suganya Chandrakumar 100343762. What Microbe Are You?. Killer Microbe. Before we start our activity… In the 1940s, the first antibiotics was developed
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Tracking the Spread of Antibiotic Resistance SBI3C: Microbiology Suganya Chandrakumar 100343762
Killer Microbe • Before we start our activity… • In the 1940s, the first antibiotics was developed • However, resistance to antibiotics is one of the greatest challenges medicine faces today • E.g. Bacteria have adapted to nearly every antibiotic
Killer Microbe Prokaryotic organisms Eukaryotic organisms Have a nucleus Most often the DNA floats freely in the cytoplasm Many bacterial cells also have additional loops, Plasmid Plasmids carry additional genes (some being antibiotic resistant) • Lack nucleus
Killer Microbe • This activity will focus on Conjugation
Antibiotic Resistance Activity! • You will each receive a paper bag that consists of 5 plasmids. (Do not reveal what’s inside your bag, or else we lose the objective of the activity!) • Paper bags represent bacterial cell; Green plasmids do not carry antibiotic resistance genes; Yellow plasmids do carry antibiotic resistance genes; arms/hands? • With the paper bags, (when I say go) you will physically move around the classroom to exchange your circles/plasmids with one another. The twist is you have to take a circle from another student’s bag without looking at it and place it in your own. • You are expected to do this 5 times.
Antibiotic Resistance Activity! After Round 1 of Exchange:
Antibiotic Resistance Activity! Round 2: And we will repeat the exchange one more time!
Antibiotic Resistance Activity! Present students with possible discussion questions: • What is the trend of antibiotic resistance as seen in this simulation? • How do you predict “bacteria” with different numbers of yellow circles might react to repeated exposure to an antibiotic? • If you have an infection and your doctor prescribe an antibiotic, why is it important to complete the full 10-14 day course of the medication, rather than to stop as soon as you start feeling better?