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 Salbutamol should be used with caution in patients with cardiovascular disease.  If used, dosing should be individualized and the therapeutic response monitored to limit side effects.  Asthma is a compelling contraindication to the use of beta-blockers as antihypertensives .

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  1. Salbutamolshould be used with caution in patients with cardiovascular disease.  If used, dosing should be individualized and the therapeutic response monitored to limit side effects. Asthma is a compelling contraindication to the use of beta-blockers as antihypertensives. Metoprolol may worsen the symptoms of heart failureandreduce the effects of salbutamol. An alternative drug that can be used is Nebivolol. It is a third-generation beta-1 selective blocker that is approved for treatment of hypertension. Nebivolol shows similar efficacy in treating hypertension, and with better tolerability. recommendations

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