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Real-Time Bone Drilling Monitoring February 2008

Real-Time Bone Drilling Monitoring February 2008. The Team. Jacob Halevy-Politch, D.Sc., E.E., CEO Technion–Israel Institute of Technology, Rafael Israel Armaments Development Authority, Israel Air Force D. Todd Dollinger, Chairman JetGuide board, The Trendlines Group

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Real-Time Bone Drilling Monitoring February 2008

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  1. Real-Time Bone Drilling Monitoring February 2008

  2. The Team • Jacob Halevy-Politch, D.Sc., E.E., CEOTechnion–Israel Institute of Technology, Rafael Israel Armaments Development Authority, Israel Air Force • D. Todd Dollinger, ChairmanJetGuide board, The Trendlines Group • Prof. Dan AdamDepartment of Biomedical Engineering, Technion-Israel Institute of Technology • Andrei Craft, D.D.S. Oral and maxillofacial surgeon, formerly Rambam Medical Center (Israel) and Toronto University Dental School • Dr. Nahum Rosenberg, M. Ortho.Orthopedic Department, Rambam Medical Center • Steve RhodesCEO, Misgav Venture Accelerator, and Chairman, The Trendlines Group

  3. Blind Man’s Bluff

  4. Vision and Markets Safe and Accurate Bone Drilling • Orthopedic/spine: • >6% growth • >$30 billion • Other surgical growth rates up to 15% • ENT: ~$5 billion • Neurosurgery: spine and skull ~$6 billion • Plastic surgery: ~$5 billion • Oral surgery • 2 million implants performed annually; $2.4 billion • Growth: 15-18% • Untapped market: implants 10% of tooth replacements

  5. Value Proposition Surgeons Real-time intraoperative feedback during surgery builds confidence and raises comfort levels. More surgeons can perform procedures. Healthcarepayors Reduction in complications for decreased costs Patients Improved outcomes andfaster procedures

  6. Water container Transmitter Pump Switch Receiver Water stream Signal processing JetGuide Electronic Unit JetGuide cell Display JetGuide ultrasonic transducer Dental implant drill Water jet stream Drill tip The JetGuide Dental System Implantology

  7. Jet stream (water) Transmitted ultrasonic waves Reflected ultrasonic wave Bore Bone Mandible canal & nerve JetGuide-measured distance to sensitive tissue a How It Works Water-Guided Ultrasonic Waves

  8. Competition

  9. Competitive Advantages • Accurate • Real-time • Simple to use • Safe • Affordable • Compact

  10. Business Development

  11. Achievements • IP • Patents strategy – patents applied for; continuing applications • Technology/Science • Operating system, algorithms, display, ultrasound cell operational • Successful experiments on phantoms and ex-vivo fresh animal bones • IRB and Ministry of Health approvals for human trials • Clinical trials under way – Rambam Medical Center, Haifa • Business Development • Established Scientific Advisory Board • On-going talks with leaders in ortho and dental markets • Regulatory • FDA pre-ruling received • Regulatory strategy, filing in process

  12. Scientific Advisory Committee • Professor Nachum SametAssistant Professor of Restorative Dentistry & Biomaterials Sciences, Harvard School of Dental Medicine • Professor M. SilbermannFormer Chief Scientist, Ministry of Health; Dean, School of Medicine, Technion-Israel Institute of Technology; Chair, Dept. of Anatomy • Professor Peter BirekInternationally recognized expert in dental Implantation and Osseo integration; Dental School, the Univ. of Toronto, Canada. • Professor M. ZaarurChief, Dept. of Neurosurgery, Rambam Hospital; School of Medicine, Technion • Dr. Micha Peled, M.D., D.D.S.Chief, Oral and Maxillofacial Surgery, Rambam Hospital; School of Medicine, Technion-Israel Institute of Technology

  13. Financial Projections

  14. Opportunity JetGuide seeks $2 million for: • Advanced product development • Clinical trials • Initial production • Business development • JetGuide Ortho – new markets

  15. JetGuide Ltd. Jacob Halevy-Politch, CEO JetGuide Ltd. Telephone: +972. 52.353-7294 E-mail: yapo@jet-guide.com Web: www.jet-guide.com

  16. Development Plan

  17. About JetGuide • September 2005: joined Misgav Venture Accelerator • Funding to Date • The Office of the Chief Scientist of the Israel Ministry of Industry, Trade & Labor • The Trendlines Israel Fund • Founders

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