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03-Heredity & Environment. Genes. DNA (deoxyribonucleic acid) The basis of heredity Chromosome Molecule of DNA Make up chromosomes Humans = 46 (23 pairs) of chromosomes Genes = Section of chromosomes Allele = Slight normal variation in a gene. Genome = Code for making an individual.
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Genes • DNA (deoxyribonucleic acid) • The basis of heredity • Chromosome • Molecule of DNA • Make up chromosomes • Humans = 46 (23 pairs) of chromosomes • Genes = Section of chromosomes • Allele = Slight normal variation in a gene
Genome = Code for making an individual • 20,000 genes (99% in other creatures also) • Genotype = The full set of genes for a specificorgasmorganism (entire genetic inheritance) • Phenotype • What you look like based on your genes • Appearance, personality, intelligence • Genotype = Hidden in your genes • Phenotype = Observable characteristics based on genes – E.g. brown eyes
Gamete Sperm Ovum (egg) Each has23 chromosomes (one half of 46)
Zygote Single cell from two gametes
Male or female? 23rd pair of chromosomes Female = XX Male = XY
Twins • Monozygotic (identical) twins • From one zygote • Share 100% genes • Dizygotic (fraternal) twins • Two sperm penetrating two ova • Share 50% of their genes
ART = Assisted Reproduction Technology • IVF = In Vitro Fertilization • Sperm mixed with ova in glass dish • Viable embryos implanted • ICSI (Intracytoplasmic sperm injection) • Intrafallopian sperm injection
One cell to many How genes interact Genotype = Entire set of genes (about 20,000) Phenotype = Appearance (blue eyes) and behavior (alcoholic)
Genotype to phenotype • How genes affect appearance and behavior • Genes + Environment = Phenotype (Appearance & behavior) • E.g. Alcoholism • Genes(Varies in intensity) + Environment (Encourages or discourages drinking) = Result
Epigenetic • All characteristics are determined by both genes and environment • E.g. height and nutrition
Additive heredity • Some alleles (gene variations) combine to affect appearance and behavior
Dominant – recessive heredity Dominate genes are more influential than recessive genes. E.g. Brown eyes (Mother-dominate) + Blue eyes (Father-recessive) = Brown eyed child Being a carrier for blue eyes can effect this
Genetic (chromosomal) abnormalities • Most often related to age of mother • Extra chromosome • E.g. Down Syndrome = 47 chromosomes
Abnormalities of the 23rd. Pair • Humans have 44 chromosomes + one X + an “X” or ”Y” • Embryos do not develop without one X • Missing chromosome • E.g. XO • Three sex chromosomes • XXY • XYY • Appear normal until puberty
Genetic Counseling Find harmful conditions Affect insurance coverage Jeopardize the marriage