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Community Pharmacists Monitoring of Pulmonary Tuberculosis Outpatients (Preliminary Study)

Community Pharmacists Monitoring of Pulmonary Tuberculosis Outpatients (Preliminary Study). Authors. Usasiri Srisakul, M.Sc. in Pharm (Clinical Pharmacy) Phayom Sookaneknun, PharmD Sunantha Osiri, Ph.D Institution : Faculty of Pharmacy and Health Sciences,

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Community Pharmacists Monitoring of Pulmonary Tuberculosis Outpatients (Preliminary Study)

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  1. Community Pharmacists Monitoring of Pulmonary Tuberculosis Outpatients (Preliminary Study)

  2. Authors Usasiri Srisakul, M.Sc. in Pharm (Clinical Pharmacy) Phayom Sookaneknun, PharmD Sunantha Osiri, Ph.D Institution: Faculty of Pharmacy and Health Sciences, Mahasarakham University, Thailand, 44150 Study funded by: Health Systems Research Institute (HSRI), Thailand

  3. Introduction • DOTS (Directly Observed Treatment, Short Course) for pulmonary tuberculosis (PulTB) is a major strategy in the National Tuberculosis Programme (NTP) following WHO global plan. • Thailand ranked the 16th in 22 high-burden countries.

  4. Objectives • To compare clinical outcome between • Community pharmacists monitoring patients • Control patients receiving normal care

  5. Method • Quasi experimental study design • Patients: • Pulmonary Tuberculosis (PulTB) without HIV co-infection • DOT category 1 (2HRZE + 4HR) • December 2002 – January 2004 • Mahasarakham provincial hospital • Preliminary study: • December 2002 – October 2003 • N = 54

  6. PulTB with DOT category1 N=54 Completed intensive treatment phase 2nd month Volunteered Community pharmacists monitoring group N=27 Control group N=27 3rd– 5th month Clinical outcomes 6th month Figure 1 Research procedure

  7. Method (cont.) • Community Pharmacists monitoring group • Refill of DOTS medication (1-4 weekly follow up) • Pharmaceutical care • Control group • Normal care from the hospital (1-3 monthly follow up) • Clinical outcomes • Cure rate • Treatment success rate • Default rate • Failure rate

  8. Results: Demographic data No significant differences in all demographic data betweent both groups.

  9. Results: Clinical outcomes * Significant differences

  10. Results: Clinical outcomes 0.022* 0.054 0.043* 0.313 Figure 2 Clinical outcomes

  11. Discussion • Community pharmacist monitoring can improve treatment succes rate (WHO goal > 85%), decrease default and failure rate • Show the community pharmacist involvement in DOTS multidisciplinary team • In the future study should be expanded number of patients, community pharmacy setting and referral system

  12. Conclusion • Community pharmacist involvement in a DOTS multidisciplinary team improved clinical outcomes in pulmonary tuberculosis outpatients.

  13. Thank you very much

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