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Respiratory Pathogens. BacterialActinobacillus pleuropneumoniaActinobacillus suis Bordetella bronchisepticaHemophilus parasuisMycoplasma hyopneumoniaePasteurella multocidaSalmonella cholerasuisStreptococcus suis. ViralPorcine Circovirus - Type 2 Porcine Respiratory and Reproductive Syndrom
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1. Respiratory Diseases in Finisher Swine: Learning as You Go Brian Payne, DVM
Bethany Swine Health Services
Sycamore, IL
2. Respiratory Pathogens Bacterial
Actinobacillus pleuropneumonia
Actinobacillus suis
Bordetella bronchiseptica
Hemophilus parasuis
Mycoplasma hyopneumoniae
Pasteurella multocida
Salmonella cholerasuis
Streptococcus suis Viral
Porcine Circovirus - Type 2
Porcine Respiratory and Reproductive Syndrome Virus
Pseudorabies Virus
Swine Influenza Virus
Parasite
Ascarids
Toxoplasmosis
Other
Fe Deficiency
Fumonisin
3. Respiratory Disease Clinical Signs Coughing
Sneezing
Thumping
Abnormal snout growth CNS signs
Tear-stained eyes
Fevers
Lethargy
Decreased intake/ADG
Poor F:G
Decreased water consumption
Mortality
4. Respiratory Disease Triggers Pathogen overload
Ventilation stress
Temperature, gasses and humidity
Social stress
Overcrowding, mixing and moving
Health stress
Concurrent diseases, immune suppression
Nutritional stress
Malnutrition
Genetic selection and growth
5. Case Study # 1
6. Case Study # 1 You get a phone call from a producer:
“I am starting to see a lot of coughing and thumping. A couple died in the past week and two this morning”
7. And by the time you get there…in 2 hours
8. What Do You Do? Just like in school, you need to know/complete the basics:
History
Walk-through (P.E.)
Diagnostics
Treat
Reassess
Learn from your successes/failures
9. History What age/size are the pigs?
How many are there?
What is the farm history of respiratory disease?
Are there clinical signs at the sow farm?
When were the first clinical signs?
Are they off feed? Water?
10. History (cont.) What is the vaccination history?
What is the treatment history?
Feed? Water? Injectable?
Has the producer performed necropsies?
What has the weather been?
Any malfunctions in the building environment? (Check highs/lows)
11. Walk Through
12. Walk Through This is your clinical exam
View the room quietly before you enter
Watch the pigs
Listen to the pigs
13. Case Study # 1
14. Necropsy
16. Necropsy
17. Case Study # 1 Histopathology Results:
Bronchointerstitial pneumonia
Multifocal suppurative necrosis of lungs
Reactive lymph nodes
Virology: neg for PRRS, SIV, PCV2
Bacteriology:
Cultured Actinobacillus pleuropneumonia
18. Case Study # 1 Penicillin and Excenel
Susceptibilities:
Broad-spectrum
Withdrawal Period
Penicillin – 15 days
Excenel® – 4 days
19. Case Study # 1 How did we do?
This one was a success
Death loss to a minimum;
Only 2 more died as a result of APP
Prevention
Increase air flow
With pigs that are APP positive, always provide fresh air
Stale air will trigger clinical signs
20. Case Study # 2
21. Case Study # 2 2 site production system
Sow center – Breed to Wean
Family farm
Single nursery
Two finishers
All confinement
22. Case Study # 2 Pig Flow 1,500 head groups every 8.5 weeks
Weaned into nursery
8 weeks in nursery
Moved to either F1 or F2 on rotational basis
~ 17 weeks in the finisher
Total days to market 170 days
23. Case Study # 2 Turns #34 and #35 had less than desirable performance (ADG and F:G)
Mortality remained ~3.5-4.0%
At the time, no notable clinical signs throughout the nursery, grower and finishing stages
At least from what I knew then!
24. Case Study # 2Wean-to-Finish ADG
25. Case Study # 2Wean-to-Finish F:G
26. Case Study # 2 Group #36 occupies F2
Hogs have been on site for 135 days
How many days until average days to market?
35 days, but 1st group will be marketed in 20 days
This is the second group to get a mild cough right around this age
During early 2006 we had a lot of H1N1 SIV going through the area
Caused a mild cough and off-feed for about 2 days
Other than that, it seemed harmless
My assumption the previous and current group were infected with SIV
27. Case Study # 2 The cough progressed to a very deep cough, lingered for 1 week, now day 145 on feed
Thumping pigs
Necropsy
28. Case Study # 2 What do you do?
Diagnostics
What are you looking for?
Which pig(s) do you want to sample?
What samples do you take?
What tests do you request?
29. Dx-Lab Results Mycoplasma PCR positive on lung tissue
Histopathology of lungs determined to be caused by a bacterial pathogen
Mononuclear infiltration (bronchi and vessels)
Bronchointerstitial pneumonia
Non-specific
SIV PCR negative
No other significant findings
30. How to treat this group? Mass medicate?
Individual treatments?
31. Prevention Strategy Vaccinate
Choosing a product
Choosing the correct timing
Choosing a dosing program
Pulse medication
Choosing a product
Choosing the time
32. How Did We Do? Mortality was never an issue
Vaccination with 1 dose of commercial Mycoplasma vaccine has been a success
Monitoring water consumption was useful on the following group (#37) as they were not vaccinated
Decreased water consumption 1-2 days prior to any clinical signs
Immediately medicated with Lincomycin soluble
33. Case Study # 2Wean-to-Finish ADG
34. Case Study # 2Wean-to-Finish F:G
35. Case Study # 2 It looked like flu!
It sounded like flu!
Therefore, it must be…
Mycoplasma
36. Case Study # 2 Conclusions What is a clinical sign?
We are trained to view the animal
Look beyond the pig
Daily intake and feed delivery
Water consumption
Don’t assume that because 1 disease is running through your practice area that because your client’s case looks similar to the others that it is that same ‘ole disease
37. Feel Free To Contact Me Brian Payne, DVM