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Contributing Authors Kyoko Besho MD. Yuko Shono MD. Y ｏ shimasa Nakai MD.

Yoshihide Nakai M.D. Intravitreal Injection of Triamcinolone and Bevacizumab During Cataract Sugery. Tokai eye clinic 399 Hadokoro-cho Tsu, Japan tokaieye@mint.or.jp. Contributing Authors Kyoko Besho MD. Yuko Shono MD. Y ｏ shimasa Nakai MD. Purpose. Triamcinolone and Bevacizumab were

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Contributing Authors Kyoko Besho MD. Yuko Shono MD. Y ｏ shimasa Nakai MD.

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  1. Yoshihide Nakai M.D. Intravitreal Injection of Triamcinoloneand Bevacizumab During Cataract Sugery Tokai eye clinic 399 Hadokoro-cho Tsu, Japan tokaieye@mint.or.jp Contributing Authors Kyoko Besho MD. Yuko Shono MD. Yｏshimasa Nakai MD.

  2. Purpose Triamcinolone and Bevacizumab were intravitreallyadministered to patients with posterior Uveites andthose with diabetic/BRVO-associated macular edema, respectively and efficacy of the drug injectionduring cataract surgery was evaluated. So the result will be reported.

  3. Material / Methods Pars plana injection of drugs were made into the vitreous cavity following 2mm incision, phacoemulsification and cataract extration. Pars plana injection

  4. Triamcinolone 4mg administered Posterior uveites : 7eyes/5patients Bevacizumab 1mg administered Diabetic macular edema : 14eyes/11patients BRVO : 8eyes/8patients 29eyes/24patients Anterior chamber flare ：Kowa Laser Flare Macular thickness ：Zeiss,Cirrus HD-OCT.

  5. (log MAR) 1.4 1.2 1.0 20/200 0.8 0.6 0.4 20/50 0.2 Result Visual acuity (BCVA) Before Surgery 7days After Surgery 29eyes/24patients Mean Visual acuity,7days after cataract surgery Improved 20/50 for 29eyes

  6. Result (log MAR) 1.4 1.2 20/250 1.0 Visual acuity (BCVA) 0.8 0.6 20/80 0.4 20/60 20/40 0.2 7days Surgery 30days surgery Before Surgery 1day After Uveites 7eyes/5patients Uveites, mean visual acuity, before surgery mean 20/250, one day after surgery It improved to 20/80, 7days 20/60 and 30days 20/40.

  7. pc/ms 100 65±18 33±19 34±11 20±14 50 Before Surgery 1day After 7days Surgery 30days surgery Result Laser Flare call Meter Anterior Chamber flare Uveites 7eyes/5patients The mean flare in anterior chamber was 33pc/ms before surgery, 65pc/ms 1day after surgery, but improved to 34pc/ms 7days after, and 20pc/ms 30days after.

  8. (log MAR) 1.4 1.2 1.0 0.8 20/150 0.6 0.4 20/50 0.2 20/40 20/30 7days Surgery 30days surgery 1day After Before Surgery Result Visual acuity (BCVA) BRVO-Macular edema 8eyes/8patients BRVO, mean visual acuity, before surgery was 20/150, but improved after 1day to 20/50, 7days after 20/40 and 30days after 20/30.

  9. μm 400 300 200 ３４４ 100 ２６５ ２２２ １９７ Before Surgery 1day After 7days Surgery 30days surgery Result OCT(Cirrus HD-OCT) Macular Thickness BRVO-Macular edema 8eyes/8patients BRVO, the mean macular thickness, before surgery 344μm, but decreased after 1day to 265μm, 7days after 222m, 30days after 197μm

  10. (log MAR) 1.4 20/400 1.2 1.0 0.8 0.6 20/80 0.4 20/50 20/40 0.2 7days Surgery 30days surgery Before Surgery 1day After Result Visual acuity (BCVA) Diabetic macular edema 14eyes/11patients Diabetic macular edema, mean visual acuity before surgery was 20/400, but one day after surgery it improved to 20/80, 7days after 20/50 and 30days after 20/40.

  11. μm 400 300 200 ３９１ ２９９ ２４９ 100 ２２３ Before Surgery 1day After 7days Surgery 30days surgery Result OCT (Cirrus HD-OCT) Macular Thickness Diabetic macular edema 14eyes/11patients Diabatic macular edema, the mean macular thickness, before surgery was 391μm but after 1day of surgery it decreased to 299μm, 7days 249μm, and 30days 223m.

  12. Conclusion It was concluded that pars plana injection of the drug during cataract extraction by phacoemulsification was effective for the improvement of postoperative visual acuity of patients with prolonged uveites and with diabetic/BRVO-associated macular edema.

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