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The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor.
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pdgfd pdgfd Official Full Name Official Full Name platelet derived growth factor D Background Background The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. Synonyms Synonyms PDGFD; platelet derived growth factor D; platelet-derived growth factor D; IEGF; MSTP036; SCDGF B; spinal cord derived growth factor B; PDGF-D; iris-expressed growth factor; spinal cord-derived growth factor B; spinal cord-derived growth factor-B; SCDGFB; SCDGF-B Recombinant Recombinant Protei Proteins ns Cell & Tissue Lysates Cell & Tissue Lysates Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price PDGFD-1611H Recombinant Human PDGFD, His-tagged E. coli Human His +Inquiry PDGFD-207H Recombinant Human PDGFD, His tagged HEK293 Human His +Inquiry PDGFD-211H Recombinant Human PDGFD NS0 Human N/A +Inquiry
Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price PDGFD-24H Recombinant Human PDGFD protein CHO Human +Inquiry PDGFD-12569M Recombinant Mouse PDGFD Protein Mammalian Cells Mouse His +Inquiry Pdgfd-390M Recombinant Mouse Pdgfd protein, His/SUMO-tagged E. coli Mouse His/SUMO +Inquiry PDGFD-4339R Recombinant Rat PDGFD Protein Mammalian Cells Rat His +Inquiry Pdgfd-8157R Recombinant Rat Pdgfd protein, His & T7-tagged E. coli Rat His/T7 +Inquiry PDGFD-5169C Recombinant Chicken PDGFD Mammalian Cells Chicken His +Inquiry PDGFD-7140H Recombinant Human Platelet Derived Growth Factor D, His-tagged E. coli Human His +Inquiry Involved Pathway PDGFD involved in several pathways and played different roles in them. We selected most pathways PDGFD participated on our site, such as Ras signaling pathway, Rap signaling pathway, Phospholipase D signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDGFD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Name Pathway Related Protein Pathway Related Protein Ras signaling pathway GRIN1; FGF20; PRKACA; FGF21; RELA; FGF17; FGF5; FGF7; PDGFRB; VEGFC Rap signaling pathway
SRC; ARAP3; PLCG1; Pdgfa&Pdgfb; KRAS; FGF13; RAP1A; FGF1; ACTB; RASSF5 Phospholipase D signaling pathway AKT1; GRM4; MS4A2; SPHK1; RRAS; GAB1; INS2; RHEB; DNM3; AVPR1B PIK-Akt signaling pathway PHLPP2; IKBKG; BRCA1; EPOR; FGF5; ITGA3; MET; IGF1; TCL1; IFNA17 Focal adhesion COL11A1A; RAC1B; SHC2; COL6A3; PXN; LAMB2; PTENB; RAF1B; AKT3A; MYLPF Gap junction TUBA3C; PRKG1; HTR2B; PRKG1A; TUBA8L2; PRKACAB; GUCY1B3; GJD2; MAP3K2; GNAI2B Regulation of actin cytoskeleton CHRM5B; RAF1B; PIK3R3B; ACTG1; FGFR3; ITGA2; VCL; ITGB1B.2; MSNB; ITGAL Prostate cancer AKT2; IGF1R; GSTP1; BAD; NRAS; INS1; SMARCD1; NKX3; HSP90AB1; CPN1 Melanoma PIK3CD; FGF20; PDGFRB; PDGFD; FGF22; PTEN; MAP2K2; MET; FGF2; MITF Choline metabolism in cancer SOS1; RPS6KB1; PIK3CB; RALGDS; PCYT1A; RAC1; PPAP2B; PLD1; MAPK9; PDGFA Protein Function PDGFD has several biochemical functions, for example, growth factor activity, platelet-derived growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDGFD itself. We selected most functions PDGFD had, and list some proteins which have the same functions with PDGFD. You can find most of the proteins on our site. Function Function Related Protein Related Protein Function Function growth factor activity Related Protein Related Protein KLK1B3; GFER; GDF2; BMP1; THPO; IL34; FGF9; INHBB; IL4; CSF3 Function Function platelet-derived growth factor receptor binding Related Protein Related Protein Pdgfa&Pdgfb; PDGFA; ITGA5; TYMP; PDGFD; IL1R1; PTPRJ; PDGFAA; PDGFRB; PDGFAB