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OHS: Definition. Obesity (BMI ?30 kg/m2) Hypercapnia (PaCO2 ? 45 mmHg) Sleep-disordered breathing. Thomas Nast, The Pickwick Papers. OHS: Clinical Presentation. Middle-aged2:1 male-to-femaleExtremely obeseSignificant sleep-disordered breathing (fatigue, hypersomnolence, snoring, AM headache). OHS: Epidemiology.
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