WELCOME

1. DINATEC INC., TECHNICAL PRESS CONFERENCE STARTS AT 8:45-9:45 A.M. WELCOME BIENVENIDOS MYCOLACTOR 100% NATURAL PROBIOTIC & MYCOTOXIN BIOAGGLUTINATION & BIODEGRADATION TECHNOLOGY

2. DINATEC Diversified Nutri-Agri Technologies Inc. Presents MYCOLACTOR Advanced Living Probiotic & Natural Mycotoxin Binding Technology

3. MYCOLACTOR OVERVIEW Approximately 90 % of the intestinal flora in birds is composed of facultative lactic acid producing bacteria such as lactobacilli, Enterococcus and some strictly anaerobic bacteria. The remaining 10 % are such as Escherichiacoli, clostridium, Staphylococcus, Pseudomonas, and others. (FOX, 1988).

4. MYCOLACTOR Poultry grown in intensive production facilities are subjected to many additional types of stressors 1.Transportation from the hatchery facility to the farm 2. High production density and overpopulation 3. Vaccination programs 4. Variations in environmental temperatures 5. Pathogenic, viral, bacterial and toxicogenic field challenges

5. MYCOLACTOR Stressors have a detrimental effect in the normal balance of the intestinal flora resulting in a decreased immune response, (JIN et al., 1997). Also other important factors are affected such as: • Increased intestinal infections due to secretion of toxins, • Reduced rate of growth, • Increased feed conversion, • Reduced egg production, • Lowered fertility, • Diminished hatchability,

6. MYCOLACTOR Qualitative factors are affected as well such as the carcass quality. (bruising as seen here>>>) These problems are further exacerbated by the likely increase of opportunistic pathogenic bacteria, resultant diarrheas and anemic conditions. (FOX, 1988). Research involving plausible solutions to this problem has recently focused attention on the natural defense mechanisms that are normally available to poultry and livestock in general in their own intestinal portal tissue.

7. MYCOLACTOR MYCOLACTOR is one leading and high quality result of such intense research and investigation by DINATEC, (Diversified Nutri-Agri Technologies Inc.,) Mycolactor seeks to restore the negative effects produced via antibiotic treatments, degrade many deleterious types of mycotoxins and bacterial toxins, and to eventually replace the use of antibiotics altogether. The use of probiotics in poultry operations is gaining momentum by the day. The reason and even necessity for this is that probiotics offer a wide array of advantages that poultry operators can not afford to overlook

8. MYCOLACTOR WORKS WELL FOR CATTLE A probiotic should afford the following characteristics 1. That it contribute probiotics which are analogous to the native micro-flora of the organism. 2. That it not produce any deleterious effects nor originate from toxic substances. 3. That the micro-organisms in the probiotic have the ability to adhere easily to the intestinal wall and multiply rapidly.

9. Mycolactor is excellent for equines also MYCOLACTOR WHAT IS A unique combination of highly effective live colony forming microorganisms consisting of 150 X 106 CFM of: Saccharomyces Cerevisiae, Enterococcus faecium, Lactobacillus acidophilus, Lacobacillus casei, Lactobacillus plantarrum and Lactobacillus brevis placed in media consisting of dried brewers yeast which includes brewers’ grain (barly and wheat), oligosaccharides and cell wall extract. A 100 % natural probiotic. A 100 % natural toxin binder

10. MYCOLACTOR Natural Probiotic and Toxin Binding Technology Why use MYCOLACTOR? ⊳Producers commonly feed low levels of antibiotics for growth promotion ⊳ The feed industry is looking for alternatives to this practice because many pathogenic microorganisms are becoming resistant antibiotics ⊳MYCOLACTOR offers a viable, effective and natural alternative to the widespread use of antibiotics.

11. MYCOLACTOR What does MYCOLACTOR do? Provides a source of live, naturally occurring microorganisms as an aid in the amelioration of mycotoxicoses. Maintains a healthy microbial balance in animals. Supplements desirable organisms to newborn animals during incidences of scours at weaning and other diet changes. Helps maintain appetite. Used as part of a health maintenance program.

12. MYCOLACTOR I. How does MYCOLACTOR work? Beneficial bacteria produce a variety of organic acids and other compounds that inhibit the growth of E.coli and other intestinal pathogens. Organic acids also can serve as energy sources to the animal or other beneficial bacteria. Lactic acid bacteria produce antimicrobials that inhibit intestinal pathogens. Beneficial bacteria deconjugate bile salts inhibiting enteric pathogens.

13. MYCOLACTOR II. How does MYCOLACTOR work? Lactic acid bacteria out-compete pathogens for nutrients in the gut.( figure 1) MYCOLACTOR NUTRIENTS

14. MYCOLACTOR III. How does MYCOLACTOR work? Animals fed lactic acid-producing bacteria have an increase of activity in their immune system, improving the animal’s resistance to bacterial infections.  MYCOLACTOR NON-PATHOGENIC BACTERIA PATHOGENIC BACTERIA EPITHELIAL TISSUE INTESTINAL WALL

15. Saccharomyces cerevisiae MYCOLACTOR IV. How does MYCOLACTOR work? Beneficial bacteria produce enzymes which breakdown feedstuffs into smaller, more easily absorbed nutrients. Lactic acid bacteria reduce the level of amines in the gut which are toxic. Enterococcus faecium Lactobacillus acidophilus Lactobacillus casei

16. MYCOLACTOR V. How does MYCOLACTOR work? AGAINST MYCOTOXINS Bio-Transformation Bio-Agglutination Bio- Degradation

17. MYCOLACTOR VI. How does MYCOLACTOR work? Bio- Transformation Bio-Transformation is one of four processes involved in toxicokinetics

18. MYCOLACTOR TOXICOKINETICS

19. MYCOLACTOR VI. How does MYCOLACTOR work? Bio- Transformation • Two substances with equal toxicity and absorption may differ in hazard depending on the nature of their iotransformation.  A substance biotransformed into a more toxic metabolite (bioactivated) is a greater hazard than a substance that is biotransformed into a less toxic or even non-toxic metabolite (detoxified).

20. MYCOLACTOR VI. How does MYCOLACTOR work? Bio- Transformation What is Toxicokinetics? Toxicokinetics is essentially the study of "how a toxic substance such as a mycotoxin gets into a given physiological organism such as abody or a multicellular biological system and what happens to it in that system".  It is widely known that many pathogenic bacteria have become immune to many tyoes of antibiotics which are in many instances mycotoxins. Mycolactor has specially selected strains of Lactobacillus, E. faecium, S. cerevisiae and other technologies that Bio-Transform, (detoxify) mycotoxins.

21. MYCOLACTOR VI. How does MYCOLACTOR work? Bio- Agglutination The process by which toxic or pathogenic substances “stick” to long chain olygosacharide molecules

22. MYCOLACTOR VI. How does MYCOLACTOR work? Bio- Degradation Degaradation via enzymatic activity

23. IMPROVES HEALTH AND PERFORMANCE OF YOUR LIVESTOCK OPTIMIZED INTESTINAL FLORA EQUILIBRIUM MORE AVAILABLE NUTRIENTS BREAKDOWN OF ENDOGENOUS PROTEINS BIO-TRANSFORMATION, BIO-DEGRADATION, & BIO-AGGLUTINATION OF MYCOTOXINS MYCOLACTOR REDUCTION IN THE PRODUCTION OF TOXIC AMINES IMPROVED ABSORPTION BENEFITS CHART INHIBITION OF PATHOGENS VITAMINS ANTIBIOTICS ANTIGENS ORGANIC ACIDS INCREASED IMMUNE SYSTEM RESPONSE ACTIVE AGAINST ENDOTOXINS REDUCED pH

24. MYCOLACTOR BENEFITS EXPLANATION • Metabolizes substrates into sugars, vitamins, amino acids & proteins making them unavailable to pathogens. • Overpowers & outcompetes pathogenic bacteria. • Produces lactic acid decreasing intestinal pH, inhibiting pathogenic bacteria growth.  • Metabolizes bacteriocines which work against pathogenic • bacteria. • Increases enzymatic activity & absorption in the intestinal tract. • Produces vitamins & enzymes that degrade mycotoxins.

25. MYCOLACTOR BENEFITS EXPLANATION, cont. Promotes healthy equilibrium of the intestinal flora & resulting benefits to the animal. Produces lactic acid which elicits an Immune reponse & the production of antibodies & increased phagocytic activity. Physically precludes the possibility for other harmful bacteria to occupy the same space.

26. MYCOLACTOR COMPARATIVE CHART

27. MYCOLACTOR Guaranteed Analysis Each gram of MYCOLACTOR is guaranteed at a minimum of 150 million colony forming units, CFU’s)Saccharomyces Cerevisiae, Enterococcus faecium, Lactobacillus acidophilus, Lacobacillus casei, Lactobacillus plantarrum and Lactobacillus brevis MYCOLACTOR is placed in a media consisting of dried brewers yeast which includes brewers’ grain (barely and wheat), oligosaccharides and cell wall extract.

28. MYCOLACTOR PRODUCT SPECIFICATIONS

29. MYCOLACTOR The End … for now … We at DINATEC INC,. want to thank you for taking time to view this MYCOLACTOR presentation