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Ketogenic Diets. Highly restricted Carb intakeClaimsMobilize fat stores for energyInduce Ketosis (incomplete fat breakdown)Ketones suppress appetiteMany ketones lost through urineAmounts to
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1. Group Questions Low Carb Diets
Diabetes
LPL / Cholesterol
2. Ketogenic Diets Highly restricted Carb intake
Claims
Mobilize fat stores for energy
Induce Ketosis (incomplete fat breakdown)
Ketones suppress appetite
Many ketones lost through urine
Amounts to lostenergy
Moderates Insulin response / increases glucagon levels
3. Ketogenic Diets What actually occurs
Urinary ketone loss accounts for at most 100-150 kcal/day = 0.45 kg weight loss/month
Gluconeogenesis using amino acids from Lean body tissue (glucagon) = ? LBM
Dehydration 2O fluid loss due to ? [ketones and amines] in urine.
4. Ketogenic Diets What actually occurs (cont.)
Acidosis ? cardiac arrhythmias
? Exercise performance due to ? glycogen stores / fatigue / headache / irritability
Unfavorable blood lipid profile
70% + calories from fat not uncommon
Vitamin / mineral deficiencies
Especially w/ some pre-packaged diets
5. Ketogenic Diets Why you loose weight
Dehydration
Loss of LBM
Often consume much less food over time as you tire of the diet.
Suppression of appetite from ketosis (not necessarily a good thing?)
40/30/30 Minimum diet recommended
6. Diabetes Diet
Minimize simple carbohydrate intake
Emphasize complex / high fiber carbohydrate sources.
Pay attention to Glycemic Index of food / eat more frequent, small meals
Moderate carbohydrate intake
Consider 40/30/30
8. Diabetes Exercise w/ No Insulin
Hyperglycemia Possible
Cells will not receive needed glucose and will stimulate breakdown of glycogen stores
May risk diabetic shock if blood sugar gets to high
Ketosis likely due to increase of fat mobilization.
Diabetics should eat light snack before exercise and take small insulin dose in non-active muscle.
9. Diabetes Too much insulin
Hypoglycemia
Glucose crosses cell membrane too fast
Blood sugar drops
Diabetic coma possible
Can be fatal if sugars are not taken in to offset
10. LPL / Cholesterol LPL activity Increase
Exercise
More muscle mass involved the better
LPL is endothelially bound to capillary beds
Released with increased blood flow
Hypertrophy / Increased capillary density
Medication
Some cholesterol lowering medications have effects on LPL activity
11. LPL / Cholesterol Fate of Glycerol & FAs
Energy
Storage (Fat)
Taken up by VLDL, LDL, or HDL
LPL activity (Reverse Cholesterol Transport) VLDL ? LDL and eventually increasing HDL C.