Lab 10

1. Lab 10 Cerebellum

2. 3 1 2 4 5 9 6 10 7 8 11 12 19 13 14 20 15 16 21 17 18

3. Deep cerebellar nuclei Fastigial nucleus Interposed nuclei Dentate nucleus 3 4 5 1 Cerebellar cortex Cerebellar white mater 2

4. 1 Molecular layer 2 Purkinge cell layer 3 Granule layer Subcortical white matter 4 Are the parallel fibers of the granular cut longitudinally or tansversely? Transversely Cerebellum, cell stain

5. 1 (layer) Molecular layer 2 (cell) Purkinje cell 3 (layer) Granule layer Is this section cut longitudinally or tansversely? Transversely Cerebellar Cortex, golgi stain

6. Inferior Cerebellar peduncle 1 Inferior Olivary Nuclei 4 (nuclei) mid medulla 2 (nuclei) Olivocerebellar fibers (dark striations) 3 (fibers) Vestibular Nuc. 7 (nuclei) reticular motor nuclei in reticular formation 5 6 (nucleus) Inferior Cerebellar peduncle Vestibular Nuclei ROSTRAL MEDULLA

7. 2 (fibers) corticobulbar & corticospinal fibers cerebellothalamic fibers 5 (fibers) corticobulbar & corticospinal fibers 7 (fibers) corticopontine fibers 3 (fibers) corticopontine fibers 8 (fibers) corticopontine fibers 1 (fibers) red nucleus 4 (nucleus) corticopontine fibers 6 (fibers) 9 (nucleus) red nucleus Midbrain/Thalamus Transition

8. Pontocerebellar fibers (dark, horizontal) 1 (fibers) corticobulbar & corticospinal fibers 3 (fibers) Pontine nuclei (pale in brain slice) 4 (nuclei) middle cerebellar peduncle 5 superior cerebellar peduncle (outflow from the cerebellum) 2 Pons

9. Superior cerebellar peduncle (outflow from the cerebellum) 1 Superior cerebellar peduncle (outflow from cerebellum) 2 Midbrain

10. 1 Superior cerebellar peduncles Decussation of superior cerebellar peduncles 2 Lateral lemniscus Midbrain

11. Posterior limb, Internal capsule 1 Posterior limb, Internal capsule 3 VL nuc. VL crus cerebri with corticopontine fibers 4 (fibers) crus cerebri with corticopontine fibers 2 (fibers) Thalamus

12. 1 What kind of weighted MRI is this? T1

13. 1 What does it mean when “the tonsils herniate?” What kind of weighted MRI is this? The tonsils are the most caudal cerebellar tissues and they can bulge, or herniate into the foramen magnum. The meduallry distortion occurring with tonsillar herniation threatens respiratory drive and other essential life functions T2

14. 1 (nucleus) What kind of weighted MRI is this? T1

15. 1 (nucleus) What are the inputs & outputs of this nucleus? What kind of weighted MRI is this? Inputs to the inferior olivary nucleus: rubroolivary fibers from the red nucleus, spinal afferents and reticuloolivary fibers from the reticular formation. Outputs from the inferior olivary nuclei: olivocerebellar fibers to the contralateral cerebellum terminating as climbing fibers. T2

16. Middle Cerebellar Peduncle 1 What kind of weighted MRI is this? T1

17. Middle Cerebellar Peduncle 1 What is the source of info being sent through the middle cerebellar peduncle? What kind of weighted MRI is this? Pontine nuclei receive input from the cortex via corticopontine fibers. Pontocerebellar fibers enter the contralateral cerebellum via the middle cerebellar peduncle. T2

18. 1 What is the main source of info being transmitted to the midbrain from the cerebellum? Where does it terminate? What kind of weighted MRI is this? Cerebellorubral fibers and cerebellothalamic fibers travel in the superior cerebellar peduncle and influence UMN systems. Cerebellorubral fibers terminate in the contralateral red nucleus. Cerebellothalamic fibers terminate in the contralateral thalamus. T1

19. 1 What is a functional task shared by the fastigial nucleus & the vermal cortex? What kind of weighted MRI is this? The fastigial nucleus links vestibulocerebellar cortex and portions of the vermal cortex with vestibular and reticular nuclei of the brainstem. They share the task of influencing axial musculature. T2

20. Olivocerebellar fibers – cerebrocerebellum receives fibers from contralalteal ION Vestibular Nuclei Inf Cerebellar peduncle Inf Olivary Nucleus What is the ~location of the: Vestibular Nuclei? Inferior Cerebellar Peduncle? Inferior Olivary Nucleus? Olivocerebellar Fibers? Midrostral Medulla Level

21. Olivocerebellar fibers Vestibular Nuclei Inf Cerebellar peduncle Inf Olivary Nucleus What is the ~location of the: Vestibular Nuclei? Inferior Cerebellar Peduncle? Inferior Olivary Nucleus? Olivocerebellar Fibers? Rostral Medulla Level

22. Corticopontine fibers Corticospinal Fibers Corticobulbar fibers What is the ~location of the: Corticospinal Fibers? Corticobulbar Fibers? Corticopontine Fibers? Rostral Midbrain Level

23. Middle Cerebellar Peduncle Pontine Nuclei Pontocerebellar fibers What is the ~location of the: Middle Cerebellar Peduncle? Pontine Nuclei? Pontocerebellar Fibers? Rostral Pons Level

24. Sup. Cerebellar peduncle What is the ~location of the Superior Cerebellar Peduncle? Rostral Pons Level

25. Sup. Cerebellar peduncle What is the ~location of the Superior Cerebellar Peduncle? Rostral Pons Level

26. Sup. Cerebellar peduncle decussation What is the ~location of the Superior Cerebellar Peduncle Decussation? Pons/Midbrain Junction

27. Sup. Cerebellar peduncle decussation What is the ~location of the Superior Cerebellar Peduncle Decussation? Caudal Midbrain Level

28. Cerebellothalamic fibers Red Nucleus Red Nucleus What is the ~location of the: Red Nucleus? Cerebellothalamic fibers? Rostral Midbrain Level

29. thalamus What is the ~location of the thalamus?