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A. B. 11.7 kb. Human LRH-1-V1. Human LRH-1-V4. Human LRH-1-V5. Mouse LRH-1-V1. Mouse LRH-1-V2. Chicken LRH-1. Xenopus LRH-1. Zebrafish LRH-1. C. HUMAN V1 1 MSSNSDTGDLQESLKHGLTPI---------------------GAGLPDRHGSPIPARGRLVMLPKV 45
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A B 11.7 kb Human LRH-1-V1 Human LRH-1-V4 Human LRH-1-V5 Mouse LRH-1-V1 Mouse LRH-1-V2 Chicken LRH-1 Xenopus LRH-1 Zebrafish LRH-1 C HUMAN V1 1 MSSNSDTGDLQESLKHGLTPI---------------------GAGLPDRHGSPIPARGRLVMLPKV 45 Human V2 1 MSSNSDTGDLQESLKHGLTPI--------------------------------------------- 21 Human v4 1 -------------------------------------------------------------MLPKV 5 Human v5 ------------------------------------------------------------------ Mouse V1 1 MSASLDTGDFQEFLKHGLTAIASAPGSETRHSPKREEQLREKRAGLPDRHRRPIPARSRLVMLPKV 66 Mouse V2 1 -------------------------------------------------------------MLPKV 5 CHICKEN 1 -------------------------------------------------------------mlpkv 5 xenopus 1 -------------------------------------------------------------mlpkv 5 ZEBRAFISH 1 -------------------------------------------------------------MLPKV 5 Human v1 46 ETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCG 90 Human v2 22 ----------------------VSQFKMVNYSYDEDLEELCPVCG 69 Human v4 6 ETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCG 50 Human v5 1 -----------MATQAGQLQAKVSQFKMVNYSYDEDLEELCPVCG 34 Mouse v1 67 ETEAPGLVRSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCG 111 MOUSE V2 6 ETEAPGLVRSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCG 50 CHICKEN 6 etealglarsngeqgqmpenmqvsqfkmvnysydedleelcpvcg 50 XENOPUS 6 epealglsrshgeqghmpenmqasqfkmmgysydeeleemcpvcg 50 ZEBRAFISH 6 ESEYLGLARSHGEQGHMPGNMQAPQFKMMDYSYDEDLDEMCPVCG 50 Thiruchelvam et al Supplementary Figure 1