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Avian Influenza H5N1 Reactive Antibodies

Avian Influenza H5N1 Reactive Antibodies. BA 468x Technology Commercialization. The Team. Christopher Bush Computer Science, Entrepreneurship Kevin Irish Marketing, Multimedia, Entrepreneurship Kyle Winkler Construction Engineering Management, Entrepreneurship Dr. Manoj Pastey

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Avian Influenza H5N1 Reactive Antibodies

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  1. Avian Influenza H5N1 Reactive Antibodies BA 468x Technology Commercialization

  2. The Team • Christopher Bush • Computer Science, Entrepreneurship • Kevin Irish • Marketing, Multimedia, Entrepreneurship • Kyle Winkler • Construction Engineering Management, Entrepreneurship • Dr. Manoj Pastey • Inventor, Assistant Professor of Veterinary Medicine • Rob Schneider • Mentor, Self Employed • Sukanya Rengaswamy • Mentor, Hewlett-Packard

  3. Definition & Status What is Bird Flu? • Avian Influenza H5N1 “Bird Flu” & H7N2 virus • Found in wild ducks & geese (host) • Spread by droppings and nasal fluids • Highly pathogenic in poultry • High fatality rate Current Status • Over 150 million birds destroyed • 291 human cases / 172 human deaths • Stage 3 of 6 WHO Global Pandemic Alert Source: Foreign Agricultural Service/USDA Office of Global Analysis, April 2007http://www.who.int/csr/disease/avian_influenza/en/index.html

  4. Spread of Avian Influenza Bird Migration H5N1 Outbreaks

  5. Why License? • Global Distribution Channels • Since 2003, human cases of avian flu has been confirmed in 12 countries, and has been found in animals in 40 countries: • Speed to Market • 6 countries have reported avian influenza deaths in 2007. • Complimentary product • Diagnostic companies have a wide range of testing products. Source: WHO

  6. Our Technology • Antibodies to specifically detect the deadly H5N1 and H7N2 strains • Easy to incorporate into existing “on-site” tests • Used for chickens and humans • Results in 10 minutes • Easy to use

  7. Why We Win Current Lab Test Positive Current Field Test Positive AvianLabsAntibodies

  8. Technology Timeline 2006 2007 2008 2009 Proof of Concept Proof of Concept Prototyping Prototyping Product Intro. Product Intro. Manf. Ramp Manf. Ramp USDA Research Grant Awarded Initial R&D – 8 mo Research Potential Licensees – 2 mo Completion of R&D – 6 mo Finalize Patent Claims – 6 mo Licensee Internal Review – 2 mo Licensing Negotiations – 4 mo Initial Marketing/Sales – 6 mo Manufacturing ramp up – 8 mo

  9. Testing Market Migratory Wild Bird Testing Poultry Testing Governments/ Regulatory Agencies Governments/ Regulatory Agencies Farmers Target Market • Governments • Monitor Migratory Wild Birds • Prevent Spread into Country • Protect its citizens • Prevent Global Pandemic • Regulate Poultry Industry • Farmers • Target Market • Prevent Large Scale Economic Loss • Provides “Insurance” Policy

  10. Sales Forecast Assumptions: • 6 Billion Chickens (Asia) • 0.5% - 1.0% tested monthly • Source: Cheok Soh Hui, ICIS Chemical Business, 2006 In millions excluding “price per kit”

  11. Revenue Forecast All $ in millions Excluding “price per kit”

  12. Current Issues/Future Potential Issues Solutions • Virus Mutations • Technology IP • Lab Predictions • Escape Mutants • Currently Strengthening Claims Future Markets & Potential • Customs (Border Crossings) • All Species • Human Antivirals & Vaccines

  13. Contact Information Thank you for allowing us to present our technology. Questions or Comments? • Christopher Bush • BushC@onid.orst.edu • Kevin Irish • IrishK@onid.orst.edu • Kyle Winkler • WinkleKy@onid.orst.edu

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