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Bioenergetics & metabolism of carbohydrates, lipids, amino acids

Bioenergetics & metabolism of carbohydrates, lipids, amino acids. Biologic oxidation. 1.summary. O 2. H 2 O. Carbohydrate, lipid, etc. CO 2. ATP. mitochondrion. enzymes. The concept of the biological oxidation.  The three stages of

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Bioenergetics & metabolism of carbohydrates, lipids, amino acids

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  1. Bioenergetics & metabolism of carbohydrates, lipids, amino acids

  2. Biologic oxidation 1.summary

  3. O2 H2O Carbohydrate, lipid, etc CO2 ATP mitochondrion enzymes

  4. The concept of the biological oxidation

  5.  The three stages of biological oxidation

  6. Nutriment materials Building block molecules Stage 1 Acetyl coenzyme A Stage 2 tricarboxylic acid cycle Stage 3 Oxidative phosphorylation

  7. Nutriment materials biological oxidation energy CO2 H2O cell usage heat energy

  8. Mitochondrion oxidation system

  9. metabolism Carbohydrate, lipid, proteins H2O, CO2 FADH, NADH H2O, Mitochondrial oxidation system energy

  10.  the structure of mitochondrion Out membrane Inner membrane matrix

  11.  ATP synthase F0-F1 complex a large membrane –protein complex

  12.  respiratory chain 1. concept 2. constitutes four electron-carrier complexes

  13. 3. types NADH oxidation respiratory chain Succinate oxidation respiratory chain

  14. 4. The components & function of the each electron-carrier complexes in these two respiratorychain .A. complex Ⅰ ( NADH-Q reductase)

  15. * Riboflavin proteins structure function types

  16. * iron-sulfur proteins structure function

  17. * ubiquinone,Q (coenzyme Q) structure function

  18. B. complex Ⅱ ( succinic-Q reductase ) Fe-s reduced FAD Q AH2 A Fe-S oxidized FADH2 QH2

  19. C. complex Ⅲ • (Q-CytC reductase ) Contain: cytb562 C cytb cytc cytb566 C1 iron-sulfur proteins

  20. * cytochromes, ( cyt ) a. structure

  21. b. Classification: cytb562 cycb cytb566 C cytc C1 a cyta a3

  22. c.the differences between each cytochromes the side chain linkage with apoenzyme Light –absorption spectra

  23. d. function Single electron carriers iron in protoporphyrin prosthetic group

  24. D. complexⅣ (CytC oxidase ) Contain: cyta,a3 CuA,CuB

  25. 5. The orders of these complexes in the respiratory chain A. A. NADH oxidation respiratory chain

  26. Compose of complex • Ⅰ,Ⅲ,Ⅳ a. contain : NAD+,FMN(Fe-S), CoQ,Cytb, c1,c , aa3,Cu,O2

  27. b. order

  28. B. Succinate oxidation respiratory chain • Compose of complex • Ⅱ,Ⅲ,Ⅳ

  29. a. contain : FAD+ (Fe-S), CoQ, Cytb, c1,c , aa3,Cu, O2

  30. b. order

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