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Prior Areas of NIA-Supported Space-Related Health Research

National Institute on Aging. Prior Areas of NIA-Supported Space-Related Health Research. NIA and NASA have collaborated on numerous research activities since 1989. NIH representative and former chair, NASA Life and Microgravity Sciences and Applications Advisory Committee

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Prior Areas of NIA-Supported Space-Related Health Research

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  1. National Institute on Aging Prior Areas of NIA-SupportedSpace-Related Health Research NIA and NASA have collaborated on numerous research activities since 1989. • NIH representative and former chair, NASA Life and Microgravity Sciences and Applications Advisory Committee • Co-chair of NASA/NIH Collaborations Committee with Director, National Institute of Deafness and Other Communications Disorders • Joint sponsor of workshops focusing on the aging process and changes induced by space • NEUROLAB - Trans-NIH Research Initiative - Exercise Guide Presenter: Dr. Richard Hodes, Director Agency/Organization: National Institute on Aging - NIH

  2. National Institute on Aging Prior Areas of NIA-SupportedSpace-Related Health Research NEUROLAB • Used the Spacelab module to conduct integrated neuroscience and behavioral research • Project included national and international partners • Several NIH institutes • Other federal agencies • International agencies Launch Date: October 29, 1998 Crew: 7 Duration: 9 days

  3. National Institute on Aging Prior Areas of NIA-SupportedSpace-Related Health Research NEUROLAB cont. • Medical research included battery of tests on how the absence of gravity affects: • Balance and perception • Immune system response • Bone and muscle density • Metabolism and blood flow • Sleep

  4. National Institute on Aging Prior Areas of NIA-SupportedSpace-Related Health Research Trans-NIH Research Initiative (PA-AG00-088):“Earth-Based Research Related to Space Environment” NIA-supported research: • Study to characterize the normal degradation in balance control using the Baltimore Longitudinal Study on Aging cohort • Study of enzyme serotonin-N-acetyltransferase, regulation of melatonin, and basic sleep pattern • Study of interstitial fluid flow and bone remodeling

  5. National Institute on Aging An NIA-NASA Collaboration Exercise: A Guide from the National Institute on Aging • NASA provided funds to print additional copies of the guide and both agencies have posted the guide on their home pages • Currently available on NIA and NASA Web sites http://weboflife.arc.nasa.gov http://www.nih.gov/nia/health/pubs/nasa-exercise E xe r c i s e : A G u i d e f rom t h e N a t i o n a l I n s t i t u t e o n A g i n g

  6. National Institute on Aging Promising Areas for NIA Space-Related Health Research Collaborations Space vs. Ground-Based Research in Aging • Bone and Muscle Loss • Age- and space-related bone loss seem to have some similar causes: reduced loads due to reduced physical activity or lack of gravitational forces, hormonal changes, and reduced calcium absorption by the intestines. • Sleep and Circadian Rhythms • Aging often results in disrupted sleep patterns. On the orbiting space station, a new sunrise occurs with each 90-minute orbit.

  7. National Institute on Aging NIA Resources to Facilitate Potential Space-Related Health Research • NIA cohorts such as the Baltimore Longitudinal Study on Aging • NIA murine models of aging

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