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Areas of Space-Related Health Research

Areas of Space-Related Health Research. Using the National Center for Toxicology Research (NCTR) Operant Test Battery (OTB) to evaluate effects of motion sickness on mental-spatial tasks, and the effects of therapeutics on these tasks (collaboration with NASA-funded investigators)

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Areas of Space-Related Health Research

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  1. Areas of Space-Related Health Research • Using the National Center for Toxicology Research (NCTR) Operant Test Battery (OTB) to evaluate effects of motion sickness on mental-spatial tasks, and the effects of therapeutics on these tasks (collaboration with NASA-funded investigators) • Evaluating physical characteristics of single- and multi-wall carbon nanotubes (NCTR collaboration utilizing NASA physical/chemical instrumentation and scientific expertise) • NASA/NCTR “fingerprinting” collaborations, utilizing NASA proprietary software to develop a NCTR PC-based, parallel-distributed artificial neural network capable of identifying complex patterns of potential use: • To identify pathogens in food matrices or bioterrorism incidents, using advanced instrumentation • To analyze digital data from diagnostic medical imaging experiments Presenter: Lewis K. Schrager, MD Agency/Organization: FDA/Office of the Commissioner

  2. Promising Areas for Space-Related Health Research Collaborations and Leveraging • Research leveraging the NCTR Operant Test Battery • Evaluate physical/cognitive skills and effectiveness of therapeutic regimens during simulated motion sickness • NCTR OTB = an ideal platform for translational research • For comprehensive evaluation of the efficacy of drugs for treatment of motion sickness • For studying the effects of therapeutics expected for use in space flight on mental and coordination skills • Research leveraging NASA physical-chemical and IT capabilities to advance FDA capabilities • To develop high-throughput analysis of pathogens • To determine the potential for developing in silico diagnostics to improve disease detection (e.g., for breast and neurological cancer) • To develop innovative drug delivery systems

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