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Pre- and Post-processing for the Finite Element Model of a Cornea Final Presentation. Advisor: Craig Foster Civil and Materials Engineering University of Illinois at Chicago Graduate Students: Dipika Gongal Talisa Mohammad Nejad Daniel Kang Lindblom Math and Science Academy
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Pre- and Post-processing for the Finite Element Model of a CorneaFinal Presentation Advisor: Craig Foster Civil and Materials Engineering University of Illinois at Chicago Graduate Students: DipikaGongal Talisa Mohammad Nejad Daniel Kang Lindblom Math and Science Academy July 21, 2011 http://www.shorelinevision.com/sitepage.asp?page=cornea
Background Healthy cornea Keratoconic cornea http://bryanking.net/keratoconus-a-degenerative-disorder/ http://1.bp.blogspot.com/_Hxm5RIeMVk8/SpEXpLfplFI/AAAAAAAAGJg/W6SRmkNcnKs/s1600-h/CORNEA
Treatment – Collagen Crosslinking Riboflavin (Vitamin B2) Stroma http://www.nkcf.org/en/treatment-options/corneal-crosslinking/70-corneal-collagen-crosslinking.html http://www.infobarrel.com/Ultaviolet_Germicidal_Lights_and_Mold_Removal%3A_An_effective_requirement_for_your_Battle_against_Mold
Finite Element Analysis http://www.youtube.com/watch?v=7HfMaJJlxTE
Model of Human Cornea Three-Dimensional Modeling and Computational Analysis of the Human Cornea Considering Distributed Collagen Fibril Orientations. Pandolfi, A. and Holzapfel, G. Journal of Biomechanical Engineering. Dec. 2008, Vol. 130. 061006-1-12.
Pre-processing • Inclusion of different parameters – geometric as well as material properties
Refinement • Trade-offs between quality and speed
Processing • Matlab – computationally the most expensive part
Post-processing • Visualization of physical conditions • What causes the spiraling seen in cornea? Bron AJ (1973) Vortex patterns of the corneal epithelium. Trans OphthamolSoc U K 93: 455-472.
Stress and Strain • Compressive • Tensile • Shear http://www.youtube.com/watch?v=3pP48_CcDls&NR=1
Work Completed • Learning pre-processing software • Was not able to obtain experimental data for pre-processing • Studied programming • Worked on post-processing • Matlab • Paraview
Special Thanks • Prof. Andreas Linninger • Prof. Craig Foster • Talisa Mohammad Nejad, DipikaGongal, Bingqing Wang • University of Illinois at Chicago • NSF