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Review: Exam II. Cardiovascular Anatomy and Physiology PED 205. Exam Format:. Chapters : 12-13 Multiple Choice: 30 Identification: Intrinsic Conduction System, Blood flow through heart, Blood Vessel Cross Section Short Answer: 5 Select One Essay Question. Cardiac Anatomy:.
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Review: Exam II Cardiovascular Anatomy and Physiology PED 205
Exam Format: • Chapters: 12-13 • Multiple Choice: 30 • Identification: • Intrinsic Conduction System, Blood flow through heart, Blood Vessel Cross Section • Short Answer: 5 • Select One Essay Question
Cardiac Anatomy: • Pericardium: Visceral / Parietal • Epicardium: Also visceral pericardium • Myocardium: Cardiac muscle layer • Endocardium: Connective Tissue Heart Valves + Epithelium
Chambers and Valves: • R. Atrium Tricuspid Valve • R. Ventricle Pulmonary Valve • Pulmonary Artery Lungs • Pulmonary Vein L. Atrium • L. Atrium Mitral (Bicuspid) V. • L. Ventricle Aortic Valve • Aorta
Coronary Arteries: • Left Coronary Artery: • Origin: Left side of AORTA • Supplies: Anterior/Left Heart • Right Coronary Artery: • Origin: Rt. Side of AORTA • Supplies: Right Heart
Coronary Artery Disease: CAD • Narrowed Coronary arteries • Thrombus: Clot forms • Myocardial Infarction • Angina Pectoris • Coronary Bypass CAB), angioplasty, stents are treatments for CAD
Intrinsic Conduction System: • SA Node: 90-100 bpm • AV Node: Slows the message down • AV Bundles: (also His): • L./R. Bundle Branches: • Purkinje Fibers:
Cardiac Muscle Cells: • Striated, Branched, Intercalated Discs • Slower Action Potential than nerve or skeletal muscle cells • Voltage Gated Ca++ Channels!
Electrocardiogram: ECG P: Atrial Depolarization/contraction QRS: Ventricular Depol/Contraction T: Ventricular Repolarization
Cardiac Cycle: • Ventricular Diastole: • Ventricles relax, fill • Pulmonary/Aortic Valves close • Second Heart Sound: “Dupp” • Ventricular Systole: • Ventricles Contract – eject blood • Tri/Bicuspid valves close • First Heart Sound: “Lubb”
Cardiac Output: HR X SV • CO = HR X SV • “Emergencies” • SNS Autonomic NS • Increase HR/SV = Increase CO • “Relaxing”: • PSNS Autonomic NS • Decrease HR = Decrease CO
Baroreceptors: Pressure Emergencies • Increase CO = Increase Systolic BP • Emergency 1: Decreased Press • Increase SNS: Increased HR X SV = Increased CO • Problem 2: Increased Press • Decrease SNS: Decrease HR = Decreased CO
Chemoreceptors: Metabolism Emergencies • Emergency 1: Increased Metabolic Rate: • Increased CO2, H+ (decreased pH) • Increased SNS …CO • Problem 2: Decreased Metabolic Rate: What’s the Problem? • Decreased CO2/ H+ (increased pH) • Decreased SNS …CO
Intrinsic Regulation of the Heart: Starling’s Law • Increased Venous Return • Increased cardiac muscle stretch • Increase contraction force • Increased SV = Increased CO • Occurs without SNS/PSNS involvement • Exercise….
Arteries and Veins • Elastic, Muscular and Arterioles • Capillaries: Exchange/Diffusion/ Osmosis • Venules, Veins
Three Tunics: • Tunica Adventitia (Externa): Fibrous connective tissue • Tunica Media: Smooth Muscle and elastic connective tissue • Tunica Intima: Endothelium (forms the valves in veins
Arterial Blood Pressure • Cardiac Output: Systolic blood pressure • Vascular Resistance: Diastolic Pressure • Vessel Diameter • Blood Viscosity • Vessel Length
Pressure and Resistance • Increased Resistance = Increased Pressure • Increased Resistance = Increased Work of the Heart • Measurement: 120/80 mm Hg
Vasoconstriction: • Decreases Vessel Diameter • Increases Resistance • Increases Diastolic BP • Increases Work of Heart • Increases SBP later • SNS, Cold, Hemorrhage etc cause vasoconstriction to “rescue” vital organs
Vasodilation: • Increases Vessel Diameter • Decreases Resistance • Decreases Diastolic Pressure • PSNS, Heat, Local Exercise Demand cause vasodilation to perfuse skin, muscles for special situations
Arteriosclerosis • Limits Vasodilation • Increases Resistance • Increases Pressure • Risk Factors: • Obesity, Cholesterol, Inactivity, Smoking, Aging, Heredity
Systolic and Diastolic BP: • Systolic: Ventricular Systole • Greatest Arterial Pressure • Reflects CO and heart’s contribution to BP • Diastolic: Ventricular Diastole • Lowest Arterial Pressure • Reflects the resistance of the vessels to CO
Essay Choices: • Exercise and the Heart/Vessels • Chronic Hypoxic Vasoconstriction of the Pulmonary Arteries • The effect of Nitroglycerin on peripheral resistance, work of the heart, BP