200 likes | 601 Views
Agents That Affect Bone Mineral Homeostasis. BY S. Bohlooli, PhD School of Medicine, Ardabil University of Medical Sciences. Hormonal regulators of bone mineral homestasis. PTH Vitamin D Calicitonin Estrogens Glucocorticoids. Bone mineral homeostasis.
E N D
Agents That Affect Bone Mineral Homeostasis BY S. Bohlooli, PhD School of Medicine, Ardabil University of Medical Sciences
Hormonal regulators of bone mineral homestasis • PTH • Vitamin D • Calicitonin • Estrogens • Glucocorticoids
The hormonal interactions controllingbone mineral homeostasis
The hormonal interactions controllingbone mineral homeostasis
Conversion of 7-dehydrocholesterol to vitamin D3 and metabolism
Actions of Parathyroid Hormone (PTH), Vitamin D, and FGF23 on Gut, Bone, and Kidney
Secondary Hormonal Regulators of Bone Mineral Homeostasis • Calcitonin • Glucocorticoids • Estrogens
Nonhormonal agents • Bisphosphonates • Calcimimetics • Thiazides • Fluoride • Other drugs • Gallium nitrate • Plicamycin • Strontium Ranelate
Typical changes in bone mineral density with time after the onset of menopause