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% cpm remaining

100. 100. ARO. 90. 90. 80. 80. FRTL-5. 70. 70. 60. 60. % cpm remaining. 50. 50. 40. 40. 30. 30. 20. 20. 10. 10. 0. 0. 0. 2. 4. 6. 8. 10. 12. 14. 16. 18. 20. 0. 2. 4. 6. 8. 10. 12. 14. 16. 18. 20. Minutes. Minutes. 100. 100. 90. 90. ARO-pCMV.

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% cpm remaining

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  1. 100 100 ARO 90 90 80 80 FRTL-5 70 70 60 60 % cpm remaining 50 50 40 40 30 30 20 20 10 10 0 0 0 2 4 6 8 10 12 14 16 18 20 0 2 4 6 8 10 12 14 16 18 20 Minutes Minutes 100 100 90 90 ARO-pCMV ARO-Pax8 cl.21 ARO-Pax8 cl.8 80 80 FRTL-5 FRTL-5 FRTL-5 70 70 60 60 % cpm remaining 50 50 40 40 30 30 20 20 10 10 0 0 0 2 4 6 8 10 12 14 16 18 20 0 2 4 6 8 10 12 14 16 18 20 Minutes Minutes

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