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Explore various methods of measuring blood parameters like flow, pressure, and oxygen concentration. Learn about sensors, electrodes, amplifiers, and non-invasive techniques in biomedical engineering. Enhance your knowledge with advanced bioengineering concepts.
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Fysisk institutt - Rikshospitalet FYS 4250 REPETITION PART 1 ....and slicky tricks to prepare you for the exam...
What is a typical question? For example: Mention some different methods for measuring blood pressure, explain the different advantages, disadvantages and eventual risks associated with each method Blood flow is another interesting parameter. Describe how it is possible to measure the blood flow both invasive and non-invasively and explain the advantages, disadvantages for each method. What would be the proper requirements for an amplifier in such a measurement system? Do you know any non-invasive methods of measuring the oxygen concentration in the blood? Give a brief description of the manner of operation, sources of error and advantages/disadvantages Give a short explanation of the function of the human heart. How is it possible to detect patology in the heart function without entering the body?
What is a sensor? Image: Grimnes, Høgetveit.Biomedical Engineering Education & Advanced Bioengineering Learning: Interdisciplinary Concepts. ”A sensor is a mediator able to convert one or more measurands or physical variables into an equivalent signal variable of another type of quantity within a frame of a given unity” Pallàs-Areny, Webster, Sensors 2001
More definitions.... Image: Grimnes-Høgetveit.Biomedical Engineering Education & Advanced Bioengineering Learning: Interdisciplinary Concepts. • Sensor system: ”comprises the total signal path from the measurand to the observer and includes all sensing, conditioning and real-time processing elements in the path” • Electrode: ” An electrode is an electrochemical cell converting charge carriers from ions to electrons or vice versa. An electrode is only a half-sensor in the way that two electrodes are necessary in order to apply a current or read a potential difference in living tissue” • Probe: A ”probe is a broader concept than a sensor. A probe is often comprising multiparameter sensors (e.g. temperature) and may be held by the operator and be equipped with switches and level adjustment facilities. Example: Ultrasound probe” Source: Grimnes-Høgetveit.Biomedical Engineering Education & Advanced Bioengineering Learning: Interdisciplinary Concepts.
Pressure transducerand Wheatstone bridge Image: Grimnes-Høgetveit.Biomedical Engineering Education & Advanced Bioengineering Learning: Interdisciplinary Concepts.
Fysisk institutt - Rikshospitalet Piezoelectric transducer C=εA/x
Fysisk institutt - Rikshospitalet Photomultipliers
FYS 4250 Chapter 4 The origin of biopotentials
Membrane potential • Nernst equation for potassium K (Nor - Kalium): across a cell membrane with active channels pumping K ions into the cell.
FYS 4250 Kap.5 Biopotential electrodes
Metal / electrolyte = electron / ion transitions
Ag / AgCl Non-polarizable electrode
Fysisk institutt - Rikshospitalet FYS 4250 Kap.6 Biopotential amplifiers
Fysisk institutt - Rikshospitalet Einthoven triangle
Fysisk institutt - Rikshospitalet Wilson central terminal
Fysisk institutt - Rikshospitalet Augmented leads
Fysisk institutt - Rikshospitalet ”Driven right leg”
Fysisk institutt - Rikshospitalet Biopotentail amplifiers
Fysisk institutt - Rikshospitalet FYS 4250 Kap.7 Blood Pressure and Sound
Fysisk institutt - Rikshospitalet The circulatory system
Fysisk institutt - Rikshospitalet Typical blood pressures
Fysisk institutt - Rikshospitalet Invasive blood pressure measurement
Fysisk institutt - Rikshospitalet Harmonic analysis, Fourier
Fysisk institutt - Rikshospitalet Heart sounds
Fysisk institutt - Rikshospitalet Stethoscopes, spektrogram
Fysisk institutt - Rikshospitalet Non-invasive blood pressure
Fysisk institutt - Rikshospitalet Ultrasound measurement
Fysisk institutt - Rikshospitalet Bloodpressure, oscillometric
Fysisk institutt - Rikshospitalet Non-contact tonometry
FYS 4250 Kap.8 Measurement of Flow and Volume of blood
FYS 4250 Chapter 9 Gas Instrumentation
Figure 2 Lung volume parameters Equation 1 Compliance C = ΔV / ΔP [L/Pa, L/cmH2O]