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Carbox y Therapy. CARBOXITHERAPY. What is it?. It is a non surgical method which consists of injecting CO2 at subcutaneous level through a very fine needle (3mm) by using an equipment especially designed for regulating the gas exit with a low pressure. Characteristics of CO2.
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CARBOXITHERAPY What is it? It is a non surgical method which consists of injecting CO2 at subcutaneous level through a very fine needle (3mm) by using an equipment especially designed for regulating the gas exit with a low pressure.
Characteristics of CO2 • Non scent, colorless, soluble in water • Final product of the organic metabolism • High disolution ( 20 times more than O2 in the microcirculation) • Modest transformation in HCO3
Origen of Carboxitherapy • 1930 : France . Gas de Royat. Arteriopaties • 1930 : Argentine Medical Association • 1953: Publication of 20 experienced years with subcutaneous injections
Action mecanisms. • Active Vaso-dilatation • Increment of oxidatve phenomena • Arteriolization of blood (Bohr effect) • Increasing of cellular oxygenation • Lipolitic effect • Sympatic-litic effect
Toxicity • Absence of toxicity with high dose • Absence of increment in the systemic TA • No variations in the systemic partial pressure of O2 and CO2
Medical directions • Angiology: Arteriopaties, microangiopaties • Reumatology: Arthritis • Urology: Erectil disfunction by angiopaties • Dermatology: Psoriasis, ulcers related to microangiopaties.
Therapeutic directions • Vascular and artery pathologies • Acute arthritis • Sports Medicine • Healing defects
Aesthetic indications • Cellulitis • Located adiposity • Pre liposculpture • Pos lipoescuplture
Contraindications • IAM, unstable anginas • ICC • HTA • Acute tromboflebitis • Located Infections • Epilepsy • Pregnancy • Renal and respiratory insufficiencies
Treatment sessions Between 15 and 20 sessions of approximately 10 minutes each, are suggested according to the different cases. The intensity per week is 2 or 3.
Treatment protocol • The suggested dose of CO2 per member should oscillate between 100 and 200 cc. • Divide the treated zone into 4 or 6 quadrants in eah member. It is suggested not to inject more than 30 o 50 cc per zone. • It is convenient to jab in several directions. • Injections should be complemented with manual massages to spread the gas, control the efisema and dicrease the annoyance on the patient
Patient with multiple symmetrical lipomatosis; pre-surgery situation (frontal) Patient with multiple symmetrical lipomatosis; pre-surgery situation (lateral) Clinic cases
. Patient with multiple symmetrical lipomatosis; pos-surgery situation (frontal) Patent with multiple symmetrical lipomatosis; pos surgery situation (lateral) Clinic cases
Figure1. Microphotograph of the abdominal subcutaneous weave on the patient with multiple symmetrical lipomatosis : biopsy before the treatment with CO2 Figure 2. Microphotography of the abdominal subcutaneous weave on the patient with multiple symmetrical lipomatosis : biopsy after the treatment with CO2. The areas of lisis adipocitaries are evident, with conservation of the anatomic integrity of the vascular system. Microphotograph
Bibliography • Hartmann B.R., Bassenge E., Pittler M.: «Effect of carbon dioxide enriched water on the cutaneous mícrocirculation and oxygen tension in the skin of the foot». Angiology, 48, 957, 1997. • Klopstock T., Naumann M., Seibel P., et al.: «Mitocondrial DNA mutations in multiple Symmetric lipomatosis». Mol. Cell. Biochem., 17, 271, 1997. • Savin E., Bailliart O., Bonnin P., et al.: «Vasomotor effects of transcutaneous CO2 in stage. Il peripheral occlusive arterial disease». Angiology, 46, 785, 1995. • Smith P.D., Stadelmann W.K., Wassemann R.J., et al.: «Benign symmetric lipomatosis (Madelung's disease)». Ann. Plast. Surg., 41, 671, 1998. • Stavropoulos P.G., Wouboulis C.C., Trautmann C., et al.: «Symmetric lipomatoses in female patients». Dermatology, 194, 26, 1997.