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Non-Neuronal Cells of the Nervous System

Explore the role of non-neuronal cells in the nervous system, including astrocytes, oligodendrocytes, microglia, and ependymal cells. Learn about their functions, interactions, and contributions to maintaining neural health and function.

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Non-Neuronal Cells of the Nervous System

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  1. Non-Neuronal Cells of the Nervous System • Neuroglia • Can’t generate • or transmit nerve • impulses (signals)

  2. Non-Neuronal Cells of the Nervous System

  3. Central Nervous System (4 kinds of cells) • 1) Astrocytes • Provides neurons with • nutrients & energy • Physical support • Forms the “Blood:Brain • Barrier”

  4. 2) Oligodendrocytes • Secretes myelin sheaths • around the axon of • the neurons (this • directs impulse)

  5. 3) Microglia • Are like Macrophages • Scavenge cell debris • Protects from • pathogens in the brain

  6. 4) Ependymal Cells • Line the hollow cavities • (ventricles) • Secretes cerebral & spinal • fluid which acts as • ‘shock absorber’, and distributes nutrients • in the brain and spinal cord

  7. Central Nervous System

  8. A myelin system • Protects cells Peripheral Nervous System

  9. Transmission Of the Nerve Impulse

  10. Before arrival of an Action (Electric) Potential Synapse (2 cells) Page 399

  11. Action Potential opens channels that cause Calcium ions to move into the Synaptic Bulb

  12. Vesicles fuse to the Synaptic Membrane

  13. Neurotransmitters released into ‘cleft’ • Examples: • Glutamate (most common in brain) • Gamma-aminobutyric acid (GABA) • Dopamine • Acetylcholine • Epinephrine • Histamine • Serotonin • Neurotensin • Nitric Oxide • Neuropeptide Y

  14. Neurotransmitters bind to receptors in next neuron...opening Sodium channels. This initiates an Action Potential in the next Neuron.

  15. Neurotransmitters are cleared out of cleft. • By: • Diffusion • Reuptake by upper neuron • Enzymatic breakdown

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