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Hypothalamus and Pituitary. Hypothalamus and Pituitary. Hypothalamus: Part of the brain, below the thalamus Produces neurohormones , which travel along length of neurons, then through blood to the pituitary Pituitary: Located below brain Controls other glands
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Hypothalamus and Pituitary Hypothalamus: Part of the brain, below the thalamus Produces neurohormones, which travel along length of neurons, then through blood to the pituitary Pituitary: Located below brain Controls other glands Two lobes (anterior and posterior)
Thyroid Gland • Located in front of the throat • Shaped like a bow tie, or butterfly • Secretes thyroxine (T4) and triiodothyronine (T3)
Thyroid Hormones Thyroxine (T4) Triiodothyronine (T3) Can you spot the difference? Where do you get your iodine?
TRH Thyroid hormone feedback loop • TRH released by hypothalamus, stimules release of TSH in pituitary • TSH stimulates thyroid, inhibits release of TRH • Thyroxine (T4) from thyroid inhibits release of TSH TSH T4 What happens if you don’t get enough iodine?
TRH Iodine deficient goiter • TRH released by hypothalamus, stimules release of TSH in pituitary • TSH stimulates thyroid, inhibits release of TRH • Thyroxine (T4) from thyroid inhibits release of TSH • Lack of iodine prevents T4 formation, loss of negative feedback on TSH • TSH continues to stimulate thyroid TSH T4
Calcitonin • Thyroid gland also produces calcitonin, which is involved in calcium balance • Calcitonin is released in response to rising blood Ca2+ levels
Parathyroid Glands • 4 small glands on posterior side of thyroid gland • Produce parathyroid hormone (PTH) • Involved in calcium balance • Released in response to low blood Ca2+ levels
Pineal Gland • Regulates several biological rhythms • Secretes melatonin • When eyes see light, melatonin secretion is inhibited
LED Screens and Melatonin • What affect do you think LED screens on phones and tablets have on melatonin levels in the brain?