1 / 24

Measles

Measles. Franklin Jones. Measles. Franklin Jones 4/3/2012. Early History of Measles.

bryga
Download Presentation

Measles

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Measles Franklin Jones Measles Franklin Jones 4/3/2012

  2. Early History of Measles • First reports of measles date back to 700 AD, but the first scientific description was featured in Muhammad ibn Zakariya ar-Razi’s “Kitab fi al-jadari wa-al-hasbah” (The Book of Smallpox and Measles) c. 900 AD. • This account was also first distinction from smallpox and chickenpox

  3. Not just an artifcact of our grandparent’s generation

  4. Remains a threat to children of the 3rd world

  5. Symptoms a b c 3 C’s

  6. Only six structural proteins

  7. From Me(asles) to You a

  8. The virus enters a host cell

  9. From here on out…

  10. Pick an organ, any organ

  11. Clinical symptoms are present after incubation period c d

  12. Not done yet Viral shedding

  13. The virus must return to the epithelium

  14. Clinical diagnosis is most common 4 Day Fever Observation of one of the 3 C’s (cough, coryza, conjuctivits)

  15. The body fights back

  16. Treatment is not strictly palliative • Can not kill virus, but can alleviate symptoms • IV fluids • Fever medication • Antibiotics for secondary infetions (PSSE) • Vitamin A supplement • Subacute sclerosing panencephalitis (PSSE)

  17. Antibodies are able to ward off infection • Live attennuated • Edmonston B or Schwartz stains90% seroconversion -Often incorporated with rubella and/or mumps vaccine

  18. Bright Future • The Measles Initiative- collaborative effort of WHO, UNICEF, ICRC, CDC, and UN + various private and public partners • Mortality decreased by 74% between 2000 and 2007, from an estimated 750,000 to 197,000…this achieved the UN’s goal to reduce measles deaths by 90% by 2010, three years early

  19. Side effects of vaccine?

  20. Additional Links • http://www.youtube.com/watch?v=iPQZyt_EoGw- Amnest International Video • http://www.youtube.com/watch?v=v80kA_dt6EE- Histopathology of Measles-Pneumonia • http://digital.films.com.libproxy.lib.unc.edu/PortalViewVideo.aspx?xtid=35512 - BBC

  21. Picture References • Slide 1http://www.inquisitr.com/164771/measles-outbreak-spreading-across-europe/ • Slide 2- http://www.payvand.com/news/07/aug/Persian-Scientists_files/image012.jpg • Slide 3 - Bryce, Jennifer. "WHO Estimates of the Causes of Death in Children." The Lancet 365(2005): 1147-1152. Web. 28 Mar. 2012. <http://ih.stanford.edu/rosenfield/resources/WHO%20Estimates%20of%20COD%20in%20Kids.pdf>. • Slide 4 – Ibid • Slide 5a- http://newspaper.li/measles/ • Slide 5b- http://www.nlm.nih.gov/medlineplus/ency/images/ency/fullsize/2558.jpg • Slide 5c- http://www.nlm.nih.gov/medlineplus/ency/images/ency/fullsize/19322.jpg • Slide 6- Moss, William. "Global Measles Elimination." Nature 4(2006): 900-908. Web. 28 Mar. 2012. <http://www.nature.com/nrmicro/journal/v4/n12/full/nrmicro1550.html>. • Slide 7a- http://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Sneeze.JPG/300px-Sneeze.JPG • Slide 7b- Moss, William. "Global Measles Elimination." Nature 4(2006): 900-908. Web. 28 Mar. 2012. <http://www.nature.com/nrmicro/journal/v4/n12/full/nrmicro1550.html>. • Slide 8 – Yanagi, Yusuke. "Measles Virus: Cellular Receptors, Tropism and Pathogenesis." Journal of General Virology 87(2006): 2767-2779. Web. 27 Mar. 2012. <http://www.jstage.jst.go.jp/article/jsv/56/1/56_27/_article>. • Slide 9 - Moss, William. "Global Measles Elimination." Nature 4(2006): 900-908. Web. 28 Mar. 2012. <http://www.nature.com/nrmicro/journal/v4/n12/full/nrmicro1550.html>.

  22. Cont. • Slide 10 – Ibid • Slide 11b- Ibid • Slide 11c- http://www.nlm.nih.gov/medlineplus/ency/images/ency/fullsize/2558.jpg • Slide 11d- - http://newspaper.li/measles/ • Slide 12 – Moss, William. "Global Measles Elimination." Nature 4(2006): 900-908. Web. 28 Mar. 2012. <http://www.nature.com/nrmicro/journal/v4/n12/full/nrmicro1550.html>. • Slide 13- Racaniello, Vincent. "An Exit Strategy for Measles Virus." Science 334.6063 (2011): 1650-1651. Web. 27 Mar. 2012. <http://www.sciencemag.org/content/334/6063/1650.full>. • Slide 14 – http://www.google.com/imgres?q=doctor+treating+child&um=1&hl=en&sa=N&biw=687&bih=679&tbm=isch&tbnid=ThZzyS0v7XT8hM:&imgrefurl=http://www.doctorswithoutborders.org/news/article.cfm%3Fid%3D3203&docid=5fEpKNCMXdlAjM&imgurl=http://www.doctorswithoutborders.org/images/news/2008/Zimbabwe-34932.jpg&w=550&h=413&ei=vu96T_20FIzO9ATT_dmaBQ&zoom=1&iact=rc&dur=299&sig=104733455050295071052&page=2&tbnh=151&tbnw=231&start=10&ndsp=13&ved=1t:429,r:8,s:10&tx=140&ty=98 • Slide 15- Moss, William. "Global Measles Elimination." Nature 4(2006): 900-908. Web. 28 Mar. 2012. <http://www.nature.com/nrmicro/journal/v4/n12/full/nrmicro1550.html>.

  23. Cont. • Slide 17 – http://www.google.com/imgres?q=MMR&um=1&hl=en&sa=N&biw=687&bih=679&tbm=isch&tbnid=dIFhsmQJYnESSM:&imgrefurl=http://www.qcc.cuny.edu/healthServices/mmrClinics.html&docid=W3v5BNv_CSpxqM&imgurl=http://www.qcc.cuny.edu/healthServices/HSImages/mmr.jpg&w=250&h=252&ei=BfB6T6WzCYGm8gT1svz2BA&zoom=1&iact=rc&dur=385&sig=104733455050295071052&page=1&tbnh=130&tbnw=129&start=0&ndsp=12&ved=1t:429,r:1,s:0&tx=52&ty=54 • Slide 19 - http://www.cmaj.ca/content/182/4/E199/F1.large.jpg

  24. Other Sources • Moss, William. "Global Measles Elimination." Nature 4(2006): 900-908. Web. 28 Mar. 2012. <http://www.nature.com/nrmicro/journal/v4/n12/full/nrmicro1550.html> • Racaniello, Vincent. "An Exit Strategy for Measles Virus." Science 334.6063 (2011): 1650-1651. Web. 27 Mar. 2012. http://www.sciencemag.org/content/334/6063/1650.full. • Yanagi, Yusuke. "Measles Virus: Cellular Receptors, Tropism and Pathogenesis." Journal of General Virology 87(2006): 2767-2779. Web. 27 Mar. 2012. <http://www.jstage.jst.go.jp/article/jsv/56/1/56_27/_article>. • Bryce, Jennifer. "WHO Estimates of the Causes of Death in Children." The Lancet 365(2005): 1147-1152. Web. 28 Mar. 2012. <http://ih.stanford.edu/rosenfield/resources/WHO%20Estimates%20of%20COD%20in%20Kids.pdf>.

More Related