1 / 32

HUMAN SEXUAL DEVELOPMENT AND PARAPHILIAS

HUMAN SEXUAL DEVELOPMENT AND PARAPHILIAS. Prof. MUDr. Jiří Raboch, DrSc. Department of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague. sexual sexual deviations delinquents. deviant sexual delinquents. SEXUAL DEVELOPMENT.

chars
Download Presentation

HUMAN SEXUAL DEVELOPMENT AND PARAPHILIAS

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. HUMAN SEXUAL DEVELOPMENT AND PARAPHILIAS Prof. MUDr. Jiří Raboch, DrSc. Department of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague

  2. sexual sexual deviations delinquents deviant sexual delinquents

  3. SEXUAL DEVELOPMENT

  4. GONADAL DIFERENTIATION Kucinskas and Just, 2005

  5. SEXUAL DEVELOPMENT

  6. RAT´S BRAIN

  7. RAT´S SEXUAL ACTIVITY

  8. SEXUAL CENTERS IN THE HYPOTHALAMUS

  9. DIFERENTIATION OF HYPOTALAMIC NUCLEI AND EPITHELIAN OF THE 3rd. BRAIN VENTRICLE

  10. FETAL TESTOSTERONE LEVELS

  11. HOHLWEG´S EFFEKT Kiss1/kisspeptin system Kiss1 gene expression and kisspeptin protein levels in anteroventral periventricular nucleus – higher levels in females Kauffman 2009

  12. RESULTS OF HYPOTHALAMOTHOMY

  13. SEXUAL DEVELOPMENT

  14. SIGMUND FREUD1856 - 1939 • THEORY OF UNCONSCIOUNESS • PSYCHOSEXUAL DEVELOPMENT • CHILDHOOD SEXUALITY • CONFLICTS, COMPLEXES

  15. Consequences of early stress and childhood maltreatment (child sexual abuse) …The major structural consequences of early stress include reduced size of the mid-portions of the corpus callosum and attenuated development of the left neocortex, hippocampus, and amygdala… …Early stress alters the development of monoamine neurotransmitters and affects their degree of laterality… Teicher et al., 2003

  16. CUMMULATIVE FREQUENCY OF EXPERIENCES WITH FORCEFULL SEXUAL ACTIVITY174 female students and 137 male students of 1st. Medical School % age (years) Raboch, 1996

  17. REDUCTION OF BRAIN STRUCTURES DEPENDENT ON AGE OF THE CHILD Teicher et al., 2008

  18. EVOLUTIONARY REACTIVE ADAPTIVE REPARATIVE SYNAPTIC LEVEL LOCAL CIRCUITS DISTANT CIRCUITS PROLIFERATION MIGRATION DIFERENTIATION CRITICAL (SENSITIVE) PERIODS Plasticity of the brain

  19. HIPPOCAMPUS AND DEPRESSION Vaidya a Duman, 2001

  20. Neuroanatomical sex-specific differences • MALE BRAIN CONTAINS ON AVERAGE 16% NEURONS MORE • MALE CORPUS CALLOSUM IS BIGGER • FEMALE TEMPORAL CORTEX HAS ON AVERAGE 11% GREATER DENSITY OF NEURONS • THE MOST SIGNIFICANT DIFFERENCES - HYPOTHALAMUS Sickel a McCarthy, 2000

  21. Sexual diferentiation of the brain • HYPOTHALAMUS • SDN-POA (sexually dimorphic nucleus of praeoptic area) - rats • INAH 1,2,3,4 (interstitial nuclei of the anterior hypothalamus) – human beings • Bed nucleus of stria terminalis

  22. DEVELOPMENT OF HYPOTHALOAMIC SDN-POA (INAH)

  23. SEXUAL DEVELOPMENT

  24. BED NUCLEUS OF STRIA TERMINALIS DEVELOPMENT Chung et al., 2002

  25. VOLUMES OF BED NUCLEUS OF STRIA TERMINALIS MTF-T – malet to female transsexuals N=6 Zhou et al., 1995

  26. Criteria of sexual „normality“ • Adequate gender identity • PREFERENCE OF • Heterosexuality (?) • Mature object • Mutual contrived (voluntary) • Adequate interaction technique • Other…

  27. F64 Gender identity disorders • F64.0 Transsexualism • F64.1 Transvestitism of the double role • F64.2 Gender identity disorder in childhood

  28. F66 Mental and behavioral disorders connceted with the sexual development and orientation • F66.0 Sexual maturation disorder • F66.1 Ego-dystonic sexual orientation • F66.2 Sexual relationships disorder

  29. F65 Disorders of sexual preferences F65.0 – Fetishism F65.1 – Transvestic fetishism F65.2 – Exhibitionism F65.3 – Voyerism F65.4 – Pedophilia F65.5 – Sexual sadism, masochism F65.6 – Multiple disorders of sexual preferences

  30. voluntary involuntary out-patient in-patient Psychotherapy individual group CBT Sociotherapy Pharmacoterapy (estrogens) antiandrogens gestagens lithium neuroleptics LH-RH analogs Operations (?) hypothalamo-thomy castration Treatment of paraphilias

  31. THANK YOU FOR YOUR ATTENTITION

More Related