40 likes | 177 Views
SUPPL FIGURE 1. SUPPL FIGURE 2. A. B. --. Cal-A. LY294002. SUPPL FIGURE 3. CGP. CGP + ZNT. CGP + ZNT + ROL. A. B. SUPPL FIGURE 4. A. B. EXT. CAVEOLA. CAVEOLA. INT. G α s. G α s. G α i. G α s. . . β 2. β 2. β 2. β 2. P. P. P. P. AC. AC. AC. AC. . P. I-1.
E N D
SUPPL FIGURE 2 A B -- Cal-A LY294002
SUPPL FIGURE 3 CGP CGP + ZNT CGP + ZNT + ROL A B
SUPPL FIGURE 4 A B EXT. CAVEOLA CAVEOLA INT. Gαs Gαs Gαi Gαs β2 β2 β2 β2 P P P P AC AC AC AC P I-1 I-1 PP1 PP1 AKAP18 AKAP18 PKA PKA PKA PKA SERCA2 SERCA2 SR C D EXT. INT. PLB PLB PLB PLB Ca2+ I-1 I-1 PP1 PP1 AKAP18 SERCA2 SERCA2 SR