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Scott Zawko 2012.11.19 Data Blitz

Scott Zawko 2012.11.19 Data Blitz. Bioresorption and Efficacy Study. Sodium displacement of calcium. Na +. Na +. Na +. Na +. Na +. Na +. Na +. Na +. Na +. Ca 2+. Ca 2+. Na +. Calcium chelation. Na +. Na +. Na +. Na +. Na +. Na +. Na +. Na +. Na +. Ca 2+. Ca 2+. Na +.

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Scott Zawko 2012.11.19 Data Blitz

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  1. Scott Zawko 2012.11.19 Data Blitz

  2. Bioresorption and Efficacy Study

  3. Sodium displacement of calcium Na+ Na+ Na+ Na+ Na+ Na+ Na+ Na+ Na+ Ca2+ Ca2+ Na+

  4. Calcium chelation Na+ Na+ Na+ Na+ Na+ Na+ Na+ Na+ Na+ Ca2+ Ca2+ Na+ Chelator EDTA Citrate

  5. Surgical procedure

  6. Rat cecal abrasion studies

  7. Chelator treatment promotes degradation in rat carcass

  8. Rat cecal abrasion studies

  9. p < 0.000001

  10. Grade scale for adhesion severity

  11. Incidence of adhesions

  12. Swelling measurements

  13. Swelling formulas

  14. Prelim swelling measurements

  15. Prelim swelling measurements

  16. Swelling data – HA/Alg Film

  17. SR weakly correlated with thickness Pearson’s Correlation Coefficient, R = 0.58

  18. HA increases film swelling

  19. HA increases film swelling

  20. Film thickness measurements

  21. Film thickness 2.7 in 200 200 2.7 in Thickness (um) Thickness (um) 100 100 0 0

  22. Leveling is very important Top Surface Shelf Bottom Surface

  23. Not-leveled Re-leveled 200 2.7 in Thickness (um) 100 200 Thickness (μm) 0 2.7 in 100 0 1 2 3 4 5 6 7 Films

  24. Leveling is difficult 10 µm θ 2.7 in

  25. Doctor blade for film casting

  26. Doctor blade for film casting

  27. Contrast two techniques

  28. Doctor Blade Films Gap height: 750 – 1000 μm 750 μm 1500 μm 1000 μm 1.7 in 3.5 in

  29. Doctor Blade Films 200 100 Thickness (μm) 0 1 2 3 4 5 6 7 750 1000 1500 750-1000 Films Gap height (µm)

  30. Doctor Blade Films

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