More Organic Chemistry: Proteins and DNA

1. More Organic Chemistry:Proteinsand DNA

2. Proteins • Enzymes • Structural proteins • Storage proteins • Transport proteins • Hormones • Receptors • Contractile proteins • Defensive proteins.

3. Amino Acids

4. Amino Acids amino N

5. Amino Acids amino O N C O acid

6. Amino Acids amino O N C C O acid

7. Amino Acids amino O N C C O acid R

8. Amino Acids H NH2—C—COOH R

9. Amino Acids 20 different amino acids: • Polar or nonpolar • Electrically charged or not.

10. Peptide Bonds

11. Peptide Bonds

12. Peptide Bonds

13. Peptide Bonds

14. Peptide Bonds

15. Peptide Bonds

16. Peptide Bonds

17. Levels of Structure: • Primary • Secondary • Tertiary • Quaternary.

18. Primary Structure

19. Primary Structure in a hole in the ground there lived a hobbit not a nasty dirty wet hole filled with the ends of worms and an oozy smell nor yet a dry bare sandy hole with nothing in it to sit down on or to eat it was a hobbit hole and that means comfort

20. Secondary Structure Chapter One In a hole in the ground there lived a hobbit. Not a nasty, dirty, wet hole, filled with the ends of worms and an oozy smell, nor yet a dry, bare, sandy hole with nothing in it to sit down on or to eat: it was a hobbit-hole, and that means comfort.

21. Tertiary Structure

22. Quaternary Structure

23. Primary Structure

24. Secondary Structure

25. Tertiary Structure

26. Quaternary Structure

27. Protein Structure

28. Protein Structure

29. Mutant Proteins

30. Denatured Proteins

31. Nucleic Acids

32. Nucleic Acids

33. Concept Check Questions Why does a denatured protein no longer function normally?

34. Concept Check Questions A genetic mutation may change a protein’s primary structure. Why does this destroy the protein’s function?

35. Concept Check Questions In a DNA double helix, one strand has the sequence: 5’-TAGGCCT-3’ List the sequence along the other strand, clearly indicating 3’ and 5’ ends of the strand. .