1 / 10

HOX gene and Polysyndactyly

P1044 Ch 47-3. HOX gene and Polysyndactyly. B9902088 蔡明璋 B9902092 鄭子謙. 大 綱. 人類 Hox genes. HOXD. HOXA. HOXC. HOXB. 人類 Hox genes 的調控. 多指畸形 Polysyndactyly. HOXD13. Polysyndactyly. 不同基因突變而致 Ex : HOXD13 EVC gene 顯性體染色體突變 1/500 ？ 治療：. 軟組織. 骨關節. 手足生殖器症

deion
Download Presentation

HOX gene and Polysyndactyly

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. P1044 Ch 47-3 HOX gene and Polysyndactyly B9902088 蔡明璋 B9902092 鄭子謙

  2. 大 綱

  3. 人類 Hox genes HOXD HOXA HOXC HOXB

  4. 人類Hox genes的調控

  5. 多指畸形 Polysyndactyly HOXD13

  6. Polysyndactyly • 不同基因突變而致 • Ex:HOXD13 • EVCgene • 顯性體染色體突變 • 1/500？ • 治療： 軟組織 骨關節

  7. 手足生殖器症 Hand-Foot-Genital Syndrome • HOXA13之突變 • 四肢、生殖器畸形 Ex拇指 輸尿管、尿道 • 單倍體效率不足 (haploinsufficiency)

  8. Hand-Foot-GenitalSyndrome

  9. 參考資料 • Wikipedia：Hox genePolydactyly Hand-Foot-Genital Syndrome 埃利偉氏症候群 http://en.wikipedia.org/wiki/Hox_gene http://en.wikipedia.org/wiki/Polydactyly http://en.wikipedia.org/wiki/Hand-Foot-Genital_Syndrome http://zh.wikipedia.org/zh-tw/%E5%9F%83%E5%88%A9%E5%81%89%E6%B0%8F%E7%97%87%E5%80%99%E7%BE%A4 • 多指畸形 医学百科: http://www.wiki8.com/duozhijixing_37696/#10 • Hand-foot-genital syndrome: http://www.gfmer.ch/genetic_diseases_v2/gendis_detail_list.php?cat3=762

  10. The End Thank you for your attention From Neutral Evolution Forum

More Related