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Non-Polar or Hydrophobic R groups

Non-Polar or Hydrophobic R groups. Hydrophilic R groups – Neutral. Hydrophilic R groups – Acidic. Hydrophilic R groups – Basic. ( a ) Alpha Helix. ( b ) Beta Pleated Sheet. Complex protein structure mostly of a helix. DNA repairing protein – form-filling on left, structural on right.

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Non-Polar or Hydrophobic R groups

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  1. Non-Polar or Hydrophobic R groups Hydrophilic R groups – Neutral Hydrophilic R groups – Acidic Hydrophilic R groups – Basic

  2. (a) Alpha Helix

  3. (b) Beta Pleated Sheet

  4. Complex protein structure mostly of a helix

  5. DNA repairing protein – form-filling on left, structural on right

  6. RNA Polymerase

  7. tRNA or Transfer RNA – Carry amino acids to ribosome site to build proteins – the “anticodon determines which it will carry

  8. mRNA being formed from a strand of DNA by proteins

  9. HUMAN ATGCTTCCGGGCACATT...ACGAG CHIMP ATGCTTCCGGGCACATT...ACGAG RAT ATA..TCGGAGTACATCGCAACGAA HUMAN C.TCAGTGCCTGCCGGAAATCTCCC CHIMP C.TCAGTATCTGCCGGAAATCTCCC RAT CATTGGTGCCTTTTGCATGTTTGCC HUMAN ACCTGGTGGCA...ACCTACCCTTG CHIMP ACCTGGTGGCA...ACCTACCCTTG RAT ACCCATTTTCATGAACTTACCGCTT Segment of DNA from Humans, Chimps and Rats Genetic differences from 80 million years of separation compared to about 5 million years

  10. Senegal haplotype from the Atlantic Coast of West Africa Benin haplotype from Central West Africa, Angola, and Kenya Bantu haplotype from Zaire, the Central African Republic, Angola, and Kenya Asian haplotype from Eastern Province of Saudi Arabia, and Central India In the U.S., the disease occurs in 1 in every 500 African American births and 1 in every 1000-1400 Hispanic American births.Europeans have about 1in 600 chance of having at least one gene for sickle.

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