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Analysis of Pediatric Heart Transplantation: Age Distribution and Survival Rates

A comprehensive study on pediatric heart recipients from 1996 to 2003, evaluating survival rates, risk factors, and post-transplant morbidities. Explore outcomes by age ranges and key factors contributing to one-year and five-year mortality.

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Analysis of Pediatric Heart Transplantation: Age Distribution and Survival Rates

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  1. HEART TRANSPLANTATION Pediatric Recipients

  2. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS(Transplants: January 1996 - June 2003)

  3. AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART RECIPIENTS(Transplants: January 1996 - June 2003)

  4. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTSBy Year of Transplant Number of Transplants

  5. NUMBER OF CENTERS REPORTING PEDIATRIC HEART TRANSPLANTS

  6. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: < 1 Year) 1988-1995 1/1996-6/2003

  7. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 1-10 Years) 1988-1995 1/1996-6/2003

  8. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 11-17 Years) 1988-1995 1/1996-6/2003l

  9. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival (1/1982-6/2002)

  10. PEDIATRIC HEART TRANSPLANTATIONConditional Kaplan-Meier Survival(1/1982-6/2002)

  11. PEDIATRIC HEART TRANSPLANTATIONConditional Kaplan-Meier Survival for Recent Era (1/1998-6/2002)

  12. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (1/1982-6/2002) Survival (%)

  13. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (1/1982-6/2002)Age: < 1 Year Survival (%)

  14. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (1/1982-6/2002)Age: 1-10 Years Survival (%)

  15. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (1/1982-6/2002)Age: 11-17 Years Survival (%)

  16. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2002)Risk Factors For 1 Year Mortality N=2,290

  17. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2002)Risk Factors for 1 Year Mortality

  18. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2002)Risk Factors for 1 Year MortalityDonor Age

  19. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2002)Risk Factors for 1 Year MortalityRecipient Pulmonary Capillary Wedge Pressure (PCW)

  20. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2002)Risk Factors for 1 Year MortalityRecipient PA systolic

  21. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2002)Factors Not Significant for 1 Year Mortality Recipient Factors: IV inotropes, PGE, ECMO, sternotomy, history of malignancy, weight, height, dialysis, recent infection, gender, age

  22. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2002)Factors Not Significant for 1 Year Mortality Donor Factors: Gender, clinical infection, history of diabetes, height, COD Transplant Factors: Donor/recipient weight ratio, CMV mismatch, ABO identical/compatible, year of transplant, ischemia time, HLA mismatch, transplant center volume

  23. PEDIATRIC HEART TRANSPLANTS (1/1995-6/1998)Risk Factors For 5 Year Mortality N=1,234

  24. PEDIATRIC HEART TRANSPLANTS(1/1995-6/1998)Risk Factors for 5 Year Mortality

  25. PEDIATRIC HEART TRANSPLANTS(1/1995-6/1998)Risk Factors for 5 Year MortalityRecipient Age

  26. PEDIATRIC HEART TRANSPLANTS(1/1995-6/1998)Factors Not Significant for 5 Year Mortality Recipient Factors: IV inotropes, PGE, ECMO, history of malignancy, recent infection, gender, hospitalized at time of transplant, bilirubin

  27. PEDIATRIC HEART TRANSPLANTS(1/1995-6/1998)Factors Not Significant for 5 Year Mortality Donor Factors: Gender, clinical infection, history of diabetes, age, COD Transplant Factors: Donor/recipient weight ratio, CMV mismatch, ABO identical/compatible, year of transplant, repeat transplant, ischemia time, HLA mismatch, transplant center volume

  28. PEDIATRIC HEART TRANSPLANTS (1/1995-6/1998)Risk Factors For 5 Year Mortality Conditional on 1 Year Survival N=968

  29. PEDIATRIC HEART RECIPIENTS Functional Status (Follow-ups: April 1994-June 2003)

  30. PEDIATRIC HEART RECIPIENTS Rehospitalization Post-transplant(Follow-ups: April 1994 - June 2003)

  31. PEDIATRIC HEART RECIPIENTSInduction Immunosuppression (Follow-ups: January 2001 - June 2003)

  32. PEDIATRIC HEART RECIPIENTSInduction Immunosuppression (Follow-ups: January 2001 - June 2003)

  33. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression at Time of Follow-upFor follow-ups between January 2000 through June 2003 NOTE: Different patients are analyzed in Year 1 and Year 5

  34. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression Drug Combinations at Time of Follow-upFor follow-ups between January 2001 through June 2003 NOTE: Different patients are analyzed in Year 1 and Year 5

  35. POST-HEART TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Prevalence in Survivors within 1 Year Post-Transplant (Follow-ups: April 1994 - June 2003)

  36. POST-HEART TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Prevalence in Survivors within 5 Years Post-Transplant (Follow-ups: April 1994 - June 2003)

  37. POST-HEART TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Prevalence in Survivors within 7 Years Post-Transplant (Follow-ups: April 1994 - June 2003)

  38. FREEDOM FROM CAV For Pediatric Heart Recipients(Follow-ups: April 1994-June 2003)

  39. FREEDOM FROM CAV For Pediatric Heart Recipients(Follow-ups: April 1994-June 2003)Stratified by Age Group

  40. SURVIVAL FOLLOWING REPORT OF CAV For Pediatric Heart Recipients(Follow-ups: April 1994-June 2003)Stratified by Age Group

  41. FREEDOM FROM SEVERE RENAL DYSFUNCTION*For Pediatric Heart Recipients(Follow-ups: April 1994-June 2003) * Severe renal dysfunction = Creatinine > 2.5 mg/dl, dialysis or renal transplant

  42. MALIGNANCY POST-HEART TRANSPLANTATION FOR PEDIATRICSCumulative Prevalence in Survivors(Follow-ups: April 1994-June 2003)

  43. FREEDOM FROM MALIGNANCYFor Pediatric Heart Recipients(Follow-ups: April 1994-June 2003)

  44. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival Based on Prednisone Use(Transplants: April 1994 - June 2002) p = 0.02

  45. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival Based on Rejection within 1st Year (Transplants: April 1994 - June 2001) P = 0.016

  46. PEDIATRIC HEART RECIPIENTSIncidence of Hypertension between 1 and 3 Years(Transplants: April 1993 - June 2000)

  47. PEDIATRIC HEART RECIPIENTSRelationship of Rejection and CAV(Follow-ups: April 1994 – June 2003) p = 0.002 p = 0.002

  48. PEDIATRIC HEART RECIPIENTSGrowth Following Transplantation: HeightStratified by Prednisone Use at Discharge and at 1 Year

  49. PEDIATRIC HEART RECIPIENTSGrowth Following Transplantation: WeightStratified by Prednisone Use at Discharge and at 1 Year

  50. PERCENTAGE OF PEDIATRIC HEART TRANSPLANT RECIPIENTS TREATED FOR REJECTION IN 1ST YEARStratified by Type of Induction (Transplants: January 1, 2000 - June 30, 2002)

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