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Exome-seq Trio Family Design

Exome-seq Trio Family Design. Tzu L Phang PhD Robert Stearman PhD May 5, 2014. Both parents are not sick Progeny is sick Both mutations pass from both parents. Both parents are not sick Progeny is sick Mutation pass from one parents. Both parents are not sick Progeny is sick

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Exome-seq Trio Family Design

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  1. Exome-seq Trio Family Design Tzu L Phang PhD Robert Stearman PhD May 5, 2014

  2. Both parents are not sick • Progeny is sick • Both mutations pass from both parents

  3. Both parents are not sick • Progeny is sick • Mutation pass from one parents

  4. Both parents are not sick • Progeny is sick • Both mutation pass from both parents • Both mutations from the same gene

  5. Both parents are not sick • Progeny is sick • Mutation pass from Mom • Must be Chromosome X

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