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alk PROTAC

ALK is a receptor tyrosine kinase (RTK) of the IRK family, which shares a YXXXYY autophosphorylation motif within their activation loops (A-loops). In its native form of the full-length single-chain receptor, ALK is composed of 1620 amino acids. A 1030-residue extracellular region comprises multiple subdomains involving a low-density lipoprotein class A domain (LDL-A), a meprin, A5, mu (MAM) domain, and a glycine (G)-rich domain.<br>https://www.creative-biolabs.com/protac/ligand-design-for-alk-targeting-protac.htm

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alk PROTAC

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